Evidence map›Paper›PMID 35926878›Full record

ArticleThe European respiratory journal2023

Sensitisation to recombinant

Pei Yee Tiew, Jayanth Kumar Narayana, Marilynn Swee Li Quek, Yan Ying Ang, Fanny Wai San Ko, Mau Ern Poh, Tavleen Kaur Jaggi, Huiying Xu, Kai Xian Thng, Mariko Siyue Koh and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in The European respiratory journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Correlation ofInternational journal of chronic obstructive pulmonary disease · 2025
    Article
  9. Review
  10. Residential exposure toThe European respiratory journal · 2024
    Article
  11. Fungal lung disease.The European respiratory journal · 2024
    Review
  12. Article
  13. Article
  14. Lung microbiota: implications and interactions in chronic pulmonary diseases.Frontiers in cellular and infection microbiology · 2024
    Review
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

  • Commented on by
    2023
5 · Who and what money

Authors and funding

16 authors at 8 institutions in 4 countries.

Pei Yee TiewDept of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.
Jayanth Kumar NarayanaLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.ORCID 0000-0001-8794-9048
Marilynn Swee Li QuekDept of Biological Sciences, National University of Singapore, Singapore.
Yan Ying AngDept of Biological Sciences, National University of Singapore, Singapore.
Fanny Wai San KoDept of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.ORCID 0000-0001-8454-0087
Mau Ern PohDept of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Tavleen Kaur JaggiLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Huiying XuDept of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
Kai Xian ThngLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Mariko Siyue KohDept of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore.ORCID 0000-0002-1230-0129
Augustine TeeDept of Respiratory and Critical Care Medicine, Changi General Hospital, Singapore.
David Shu Cheong HuiDept of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong.
John Arputhan AbisheganadenLee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
Krasimira Tsaneva-AtanasovaLiving Systems Institute and Department of Mathematics, College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter, UK.ORCID 0000-0002-6294-7051
Fook Tim ChewDept of Biological Sciences, National University of Singapore, Singapore.ORCID 0000-0003-1337-5146
Sanjay H ChotirmallLee Kong Chian School of Medicine, Nanyang Technological University, Singapore schotirmall@ntu.edu.sg.ORCID 0000-0003-0417-7607
Nanyang Technological University · SGNational University of Singapore · SGChinese University of Hong Kong · HKSingapore General Hospital · SGChangi General Hospital · SGEngineering and Physical Sciences Research Council · GBTan Tock Seng Hospital · SGUniversity of Malaya · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVariable clinical outcomes are reported with fungal sensitisation in chronic obstructive pulmonary disease (COPD), and it remains unclear which fungi and what allergens associate with the poorest outcomes. The use of recombinant as opposed to crude allergens for such assessment is unknown.

methodsA prospective multicentre assessment of stable COPD (n=614) was undertaken in five hospitals across three countries: Singapore, Malaysia and Hong Kong. Clinical and serological assessment was performed against a panel of 35 fungal allergens including crude and recombinant

results

conclusion

Indexed as

Aspergillus fumigatusPulmonary Disease, Chronic ObstructiveAllergensAspergillusHumansImmunoglobulin EProspective StudiesAllergensImmunoglobulin E

Identifiers

PMID35926878
PMCPMC9816419
OpenAlexW4289836005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.