ArticleAmerican journal of respiratory and critical care medicine2023
Pulmonary Surfactant Proteins Are Inhibited by Immunoglobulin A Autoantibodies in Severe COVID-19.
Open access · greenAbstract read
In one paragraph
Article in American journal of respiratory and critical care medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 30 citations in OpenAlex.
- Lucinactant, a Synthetic Surfactant for the Treatment of Acute Respiratory Distress Syndrome Caused by COVID-19: Phase 1/2A Trial.JMIR formative research · 2026Trial
- Protocols in the therapeutic use of medical ozone: a matter of debate.Medical gas research · 2026Article
- Thymic alveolar type 2 epithelial mimetic cells revealed by RUNX1 deficiency.Nature immunology · 2026Article
- Recent advances in pulmonary fibrosis: from lung surfactant to the immune connection.Respiratory research · 2026Review
- Multimerization of secretory IgA enhances antiviral activity by aggregating influenza A virus particles.Communications biology · 2026Article
- Surfactant therapy for the treatment of acute respiratory distress syndrome: time to revisit?Journal of applied physiology (Bethesda, Md. : 1985) · 2026Review
- Crosstalk between the microbiome and the mucosal immunoglobulin A system in the lung, in health and disease.Frontiers in cellular and infection microbiology · 2026Review
- Anti-SARS-CoV-2 nucleoprotein IgA is associated with worse disease severity in critically ill COVID-19 pneumonia patients.Frontiers in immunology · 2026Article
- Newborns with ARDS originating from sepsis of extrapulmonary origin exhibit worse prognoses: findings from a multicenter study in China.European journal of pediatrics · 2025Article
- Conformational changes of surfactant protein B due to the alveolar air/liquid interface using molecular dynamics.Journal of molecular modeling · 2025Article
- Cell-cell crosstalk in the pathogenesis of acute lung injury and acute respiratory distress syndrome.Tissue barriers · 2025Review
- Exploring the Contrasts and Similarities of Dengue and SARS-CoV-2 Infections During the COVID-19 Era.International journal of molecular sciences · 2024Review
- Does Autoimmune Response Against Surfactant Protein Cause Interstitial Lung Disease?American journal of respiratory and critical care medicine · 2024Article
- Phage Immunoprecipitation-Sequencing Reveals CDHR5 Autoantibodies in Select Patients With Interstitial Lung Disease.ACR open rheumatology · 2024Article
- Unraveling the enigma: The emerging significance of pulmonary surfactant proteins in predicting, diagnosing, and managing COVID-19.Immunity, inflammation and disease · 2024Review
- Physiological and immunological barriers in the lung.Seminars in immunopathology · 2024Review
- Article
- Surfactant replacement therapy as promising treatment for COVID-19: an updated narrative review.Bioscience reports · 2023Review
- Immunosensors for Autoimmune-Disease-Related Biomarkers: A Literature Review.Sensors (Basel, Switzerland) · 2023Review
- Exhaled aerosols among PCR-confirmed SARS-CoV-2-infected children.Frontiers in pediatrics · 2023Article
Corrections and comments
- Commented on by
Authors and funding
45 authors at 20 institutions in 13 countries.
Tobias SinnbergDepartment of Dermatology.ORCID 0000-0003-3922-3327
Christa LichtensteigerInstitute of Immunobiology.
Omar Hasan AliInstitute of Immunobiology.ORCID 0000-0001-5185-7520
Oltin T PopInstitute of Immunobiology.ORCID 0000-0001-8000-2310
Ann-Kristin JochumInstitute of Immunobiology.ORCID 0000-0002-6981-1384
Lorenz RischCenter of Laboratory Medicine, Vaduz, Liechtenstein.ORCID 0000-0003-2692-6699
Silvio D BruggerDepartment of Infectious Diseases and Hospital Hygiene, and.ORCID 0000-0001-9492-9088
Ana VelicProteome Center Tübingen, Interfaculty Institute for Cell Biology.ORCID 0000-0001-6238-0959
David BomzeInstitute of Immunobiology.
Philipp KohlerDivision of Infectious Diseases and Hospital Epidemiology.ORCID 0000-0003-0427-8934
Pietro VernazzaDivision of Infectious Diseases and Hospital Epidemiology.ORCID 0000-0002-6849-6941
Werner C AlbrichDivision of Infectious Diseases and Hospital Epidemiology.ORCID 0000-0003-0607-7159
Christian R KahlertDivision of Infectious Diseases and Hospital Epidemiology.ORCID 0000-0002-0784-3276
Marie-Therese AbdouInstitute of Immunobiology.
Nina WyssInstitute of Immunobiology.
Kathrin HofmeisterDepartment of Dermatology.
Heike NiessnerDepartment of Dermatology.ORCID 0000-0002-2542-7022
Carl ZinnerPathology, Institute of Medical Genetics and Pathology.
Mara GilardiPathology, Institute of Medical Genetics and Pathology.ORCID 0000-0001-8730-3642
Alexandar TzankovPathology, Institute of Medical Genetics and Pathology.ORCID 0000-0002-1100-3819
Martin RöckenDepartment of Dermatology.ORCID 0000-0003-3795-7001
Alex DulovicNMI Natural and Medical Sciences Institute, and.ORCID 0000-0003-0017-6738
Srikanth Mairpady ShambatDepartment of Infectious Diseases and Hospital Hygiene, and.ORCID 0000-0002-0527-3978
Natalia RuetaloInstitute for Medical Virology and Epidemiology, and.
Philipp K BuehlerInstitute of Intensive Care Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0003-4690-9896
Thomas C ScheierDepartment of Infectious Diseases and Hospital Hygiene, and.
Wolfram JochumInstitute of Pathology.ORCID 0000-0001-6170-2020
Lukas KernLung Center.
Samuel HenzDepartment of Internal Medicine.ORCID 0000-0001-5227-6509
Tino SchneiderDivision of Pneumology, and.
Gabriela M KusterDepartment of Cardiology and Cardiovascular Research Institute Basel (CRIB).ORCID 0000-0002-8209-4631
Maurin LampartDepartment of Cardiology and Cardiovascular Research Institute Basel (CRIB).
Martin SiegemundIntensive Care Unit, Department of Acute Medicine.ORCID 0000-0002-2013-4140
Roland BingisserEmergency Department, University Hospital Basel, University of Basel, Basel, Switzerland.ORCID 0000-0001-8223-9792
Michael SchindlerInstitute for Medical Virology and Epidemiology, and.ORCID 0000-0001-8989-5813
Nicole Schneiderhan-MarraNMI Natural and Medical Sciences Institute, and.ORCID 0000-0001-6785-181X
Hubert KalbacherInstitute of Clinical Anatomy and Cell Analysis, University of Tübingen, Tübingen, Germany.ORCID 0000-0002-7862-277X
Kathy D McCoySnyder Institute for Chronic Disease, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.ORCID 0000-0002-3900-9227
Werner SpenglerDepartment of Medical Oncology and Pneumology, University Hospital Tübingen, Tübingen, Germany.
Martin H BrutscheInstitute of Intensive Care Medicine, University Hospital Zurich, University of Zurich, Zurich, Switzerland.ORCID 0000-0002-1612-3609
Boris MačekProteome Center Tübingen, Interfaculty Institute for Cell Biology.ORCID 0000-0002-1206-2458
Raphael TwerenboldDivision of Pneumology, and.ORCID 0000-0003-3814-6542
Josef M PenningerDepartment of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0002-8194-3777
Matthias S MatterCenter of Laboratory Medicine, Vaduz, Liechtenstein.ORCID 0000-0002-2005-5266
Lukas FlatzDepartment of Dermatology.ORCID 0000-0001-9683-8390
Institute of Immunology · HRGuided Therapeutics (United States) · USMedical Genetics Center · DECardiovascular Institute Hospital · JPNatural and Medical Sciences Institute · DEProteome Sciences (United Kingdom) · GBUniversity of Zurich · CHClinica de Pneumologie Iaşi · ROInstitute of Molecular Biotechnology · ATIntensive Care Society · GBLung Institute · USTaipei Institute of Pathology · TWTel Aviv University · ILUniversität Hamburg · DEUniversity of Basel · CHUniversity of Bern · CHUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Liechtenstein · LIUniversity of St.Gallen · CH
Funding
CIHR F20-02015CIHR F20-02343
Abstract
PubMed holds no abstract for this paper.
Indexed as
COVID-19Pulmonary SurfactantsAutoantibodiesBronchoalveolar Lavage FluidHumansImmunoglobulin ASurface-Active AgentsAutoantibodiesImmunoglobulin APulmonary SurfactantsSurface-Active AgentsautoimmunityCOVID-19immunoglobulin Apulmonary-associated surfactant proteinpulmonary surfactant
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.