ArticleScience (New York, N.Y.)2022
Selection against admixture and gene regulatory divergence in a long-term primate field study.
Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed.
- A tsunami of genome reshuffling.Nature ecology & evolution · 2026Article
- The Baboon as a Model to Study Human Health and Complex Disease.American journal of primatology · 2026Review
- Lifetime fitness and annual survival are heritable and highly genetically correlated in a wild primate population.Evolution; international journal of organic evolution · 2026Article
- Article
- Genetics and genomics of hybridization.Nature reviews. Genetics · 2026Review
- Activity budgets, social behavior, and fitness outcomes associated with a baboon group fusion.bioRxiv : the preprint server for biology · 2026Article
- Demographic, behavioral, and ecological data from a long-term field study of wild baboons in Amboseli, Kenya.Scientific data · 2026Article
- Admixture influences the genetic architecture of DNA methylation in a wild primate hybrid zone.Genome biology · 2026Article
- Group social conditions and environment predict foraging behavior in wild baboons.bioRxiv : the preprint server for biology · 2025Article
- Lifetime fitness and annual survival are heritable and highly genetically correlated in a wild primate population.bioRxiv : the preprint server for biology · 2025Article
- A Reassessment of the Genomic Ancestry of the World's Largest Captive Baboon Colony.American journal of primatology · 2025Article
- Demographic, behavioral, and ecological data from a long-term field study of wild baboons in Amboseli, Kenya.bioRxiv : the preprint server for biology · 2025Article
- High early lactational synchrony within baboon groups predicts increased female-female competition and infant mortality.bioRxiv : the preprint server for biology · 2025Article
- Addressing missing context in regulatory variation across primate evolution.Current opinion in genetics & development · 2025Review
- Testing early life effects frameworks: developmental constraints and adaptive response hypotheses do not explain fertility outcomes in wild female baboons.Proceedings. Biological sciences · 2025Article
- Baboons at a Crossroads: Hybridisation Events and Genomic Links of Central Mozambique's Baboons With Papio Neighbors.American journal of biological anthropology · 2025Article
- Eukaryotic composition across seasons and social groups in the gut microbiota of wild baboons.Animal microbiome · 2025Article
- Early-life paternal relationships predict adult female survival in wild baboons.Proceedings. Biological sciences · 2025Article
- Phylogenetics and genomic variation of Hepatocystis isolated from shotgun sequencing of wild primate hosts.PLoS pathogens · 2025Article
- Early-life paternal relationships predict adult female survival in wild baboons.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Genetic admixture is central to primate evolution. We combined 50 years of field observations of immigration and group demography with genomic data from ~9 generations of hybrid baboons to investigate the consequences of admixture in the wild. Despite no obvious fitness costs to hybrids, we found signatures of selection against admixture similar to those described for archaic hominins. These patterns were concentrated near genes where ancestry is strongly associated with gene expression. Our analyses also show that introgression is partially predictable across the genome. This study demonstrates the value of integrating genomic and field data for revealing how "genomic signatures of selection" (e.g., reduced introgression in low-recombination regions) manifest in nature; moreover, it underscores the importance of other primates as living models for human evolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.