Evidence map›Paper›PMID 35925972›Full record

ArticlePloS one2022

Assessing risk factors for latent and active tuberculosis among persons living with HIV in Florida: A comparison of self-reports and medical records.

Nana Ayegua Hagan Seneadza, Awewura Kwara, Michael Lauzardo, Cindy Prins, Zhi Zhou, Marie Nancy Séraphin, Nicole Ennis, Jamie P Morano, Babette Brumback, Robert L Cook

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Nana Ayegua Hagan SeneadzaDepartment of Community Health, University of Ghana Medical School, Accra, Ghana.ORCID 0000-0001-8836-7154
Awewura KwaraDivision of Infectious Diseases and Global Medicine, College of Medicine, University of Florida, Gainesville, Florida, United States of America.ORCID 0000-0002-1118-8331
Michael LauzardoDivision of Infectious Diseases and Global Medicine, College of Medicine, University of Florida, Gainesville, Florida, United States of America.
Cindy PrinsDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, Florida, United States of America.
Zhi ZhouDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, Florida, United States of America.
Marie Nancy SéraphinDivision of Infectious Diseases and Global Medicine, College of Medicine, University of Florida, Gainesville, Florida, United States of America.
Nicole EnnisDepartment of Behavioral Sciences and Social Medicine, Florida State University, Tallahassee, Florida, United States of America.
Jamie P MoranoUniversity of South Florida, Morsani College of Medicine, Tampa, Florida, United States of America.
Babette BrumbackDepartment of Biostatistics, Colleges of Public Health & Health Professions and Medicine, University of Florida, Gainesville, Florida, United States of America.
Robert L CookDepartment of Epidemiology, College of Public Health and Health Professions and College of Medicine, University of Florida, Gainesville, Florida, United States of America.
University of Florida · USFlorida State University · USUniversity of Ghana · GHUniversity of South Florida · US

Funding

Mechanisms of Behavior Change Resource Core for Alcohol-HIV InterventionsU24AA022003 · NIAAA · BROWN UNIVERSITY · PI KAHLER, CHRISTOPHER W. · 2012 to 2020
$5.9M
Together: Transforming and Translating Discovery to Improve HealthKL2TR001429 · NCATS · UNIVERSITY OF FLORIDA · PI GUIRGIS, FAHEEM W, LEEUWENBURGH, CHRISTIAAN · 2015 to 2023
$5.5M
Southern HIV and Alcohol Research Consortium Administrative and Research Support CoreU24AA022002 · NIAAA · UNIVERSITY OF FLORIDA · PI COOK, ROBERT L · 2012 to 2022
$5.5M
Training Program in Tuberculosis and HIV Research in GhanaD43TW010055 · FIC · UNIVERSITY OF FLORIDA · PI KWARA, AWEWURA JACOB · 2015 to 2019
$1.5M
Linking within- and between-host dynamics in tracking recent Mycobacterium tuberculosis transmissionK01AI153544 · NIAID · UNIVERSITY OF FLORIDA · PI SERAPHIN, MARIE NANCY · 2021 to 2025
$652k
FIC NIH HHS D43 TW010055NCATS NIH HHS KL2 TR001429NIAAA NIH HHS U24 AA022002NIAAA NIH HHS U24 AA022003NIAID NIH HHS K01 AI153544NIAID NIH HHS L30 AI146934
6 · The paper itself

Abstract

purposeThis study examined factors associated with TB among persons living with HIV (PLWH) in Florida and the agreement between self-reported and medically documented history of tuberculosis (TB) in assessing the risk factors.

methodsSelf-reported and medically documented data of 655 PLWH in Florida were analyzed. Data on sociodemographic factors such as age, race/ethnicity, place of birth, current marital status, education, employment, homelessness in the past year and 'ever been jailed' and behavioural factors such as excessive alcohol use, marijuana, injection drug use (IDU), substance and current cigarette use were obtained. Health status information such as health insurance status, adherence to HIV antiretroviral therapy (ART), most recent CD4 count, HIV viral load and comorbid conditions were also obtained. The associations between these selected factors with self-reported TB and medically documented TB diagnosis were compared using Chi-square and logistic regression analyses. Additionally, the agreement between self-reports and medical records was assessed.

resultsTB prevalence according to self-reports and medical records was 16.6% and 7.5% respectively. Being age ≥55 years, African American and homeless in the past 12 months were statistically significantly associated with self-reported TB, while being African American homeless in the past 12 months and not on antiretroviral therapy (ART) were statistically significantly associated with medically documented TB. African Americans compared to Whites had odds ratios of 3.04 and 4.89 for self-reported and medically documented TB, respectively. There was moderate agreement between self-reported and medically documented TB (Kappa = 0.41).

conclusionsTB prevalence was higher based on self-reports than medical records. There was moderate agreement between the two data sources, showing the importance of self-reports. Establishing the true prevalence of TB and associated risk factors in PLWH for developing policies may therefore require the use of self-reports and confirmation by screening tests, clinical signs and/or microbiologic data.

Indexed as

HIV InfectionsTuberculosisFloridaHumansMedical RecordsMiddle AgedRisk FactorsSelf Report

Identifiers

PMID35925972
PMCPMC9352085
OpenAlexW4289850183

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.