ArticleSurgical endoscopy2023
Outcomes of biologic versus synthetic mesh in CDC class 3 and 4 open abdominal wall reconstruction.
Article in Surgical endoscopy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Full-thickness skin and dermal grafts as abdominal wall augmentation in ventral hernia repairs - a systematic review.Hernia : the journal of hernias and abdominal wall surgery · 2026Pooled it
- Meta-analysis of controlled studies comparing biologic and synthetic unabsorbable mesh in contaminated fields.Surgical endoscopy · 2025Pooled it
- Synthetic vs. biologic mesh for abdominal wall reconstruction in contaminated surgical fields. A meta-analysis of randomized controlled trials and observational studies.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- The use of poly-4-hydroxybutyrate (P4HB, Phasix™) mesh in ventral hernia repair: a systematic review and meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2024Pooled it
- Synthetic Versus Biological Mesh in Ventral Hernia Repair and Abdominal Wall Reconstruction: A Systematic Review and Recommendations from Evidence-Based Medicine.World journal of surgery · 2023Pooled it
- Early and late outcomes of component separation with transversus abdominis release with mesh augmentation versus primary suturing for the management of abdominal dehiscence: a retrospective comparative study.World journal of emergency surgery : WJES · 2026Article
- A practical algorithm for the management of mesh infection in abdominal wall surgery: learnings after 20 years of experience.Hernia : the journal of hernias and abdominal wall surgery · 2026Article
- Bio-resorbable poly-4-hydroxybutyrate (P4HB) mesh for abdominal wall reconstruction is effective in high-risk patients and contaminated abdomen.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Collagen Remodeling of Strattice™ Firm in a Nonhuman Primate Model of Abdominal Wall Repair.Bioengineering (Basel, Switzerland) · 2025Article
- Evidence-based, cost-effective management of abdominal wall hernias: An algorithm of the Journal of Trauma and Acute Care Surgery emergency general surgery algorithms work group.The journal of trauma and acute care surgery · 2025Article
- Preoperative Botulinum Toxin A (BTA) injection in abdominal wall reconstruction for subxiphoid (M1) hernias.Hernia : the journal of hernias and abdominal wall surgery · 2025Article
- Use of Biologic and Biosynthetic Mesh for Ventral Hernia Repair in Current Practice.JAMA surgery · 2025Article
- Concurrent Panniculectomy With Abdominal Wall Reconstruction: A Propensity-scored Matched Study of Quality Improvement Outcomes.Plastic and reconstructive surgery. Global open · 2024Article
- Comparison of Medical Research Abstracts Written by Surgical Trainees and Senior Surgeons or Generated by Large Language Models.JAMA network open · 2024Article
- Deep learning model utilizing clinical data alone outperforms image-based model for hernia recurrence following abdominal wall reconstruction with long-term follow up.Surgical endoscopy · 2024Article
- Three-year follow-up of the grip concept: an open, prospective, observational registry study on biomechanically calculated abdominal wall repair for complex incisional hernias.Hernia : the journal of hernias and abdominal wall surgery · 2024Observational
- Long-Term Follow-Up of Patients Undergoing CAWR Should be Mandatory: A Call for Action.World journal of surgery · 2023Article
- Inflammatory Reaction and Formation of Adhesions after Intraperitoneal Application of Biological SIS Mesh.JSLS : Journal of the Society of Laparoendoscopic SurgeonsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAbdominal wall reconstruction (AWR) in a contaminated field is associated with an increased risk of wound complications, infection, and reoperation. The best method of repair and mesh choice in these operations have generated marked controversy. Our aim was to compare outcomes of patients who underwent AWR with biologic versus synthetic mesh in CDC class 3 and 4 wounds.
methodsA prospective, single-institution database was queried for AWR using biologic or synthetic mesh in CDC Class 3 and 4 wounds. Hernia recurrence and complications were measured. Multivariable logistic regression was performed to identify factors predicting both.
resultsIn total, 386 patients with contaminated wounds underwent AWR, 335 with biologic and 51 with synthetic mesh. Groups were similar in age, sex, BMI, and rate of diabetes. Biologic mesh patients had larger hernia defects (298 ± 233cm
conclusionsWound complications in AWR with CDC class 3 and 4 wounds significantly increased mesh infection and hernia recurrence; failure to achieve fascial closure also increased hernia recurrence. Use of synthetic versus biologic mesh increased the mesh infection rate by 18.6 times.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.