Evidence map›Paper›PMID 35925379›Full record

ArticleCardiovascular and interventional radiology2022

Using an Assumed Lung Mass Inaccurately Estimates the Lung Absorbed Dose in Patients Undergoing Hepatic

Cassidy R Dodson, Colin Marshall, Jared C Durieux, Patrick F Wojtylak, Jon C Davidson, Raymond F Muzic, Arash Kardan

Abstract read
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In one paragraph

Article in Cardiovascular and interventional radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. MIRD Pamphlet No. 29: MIRDy90-AJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Cassidy R DodsonDepartment of Radiology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Colin MarshallDepartment of Radiology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Jared C DurieuxDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Patrick F WojtylakDepartment of Radiology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.
Jon C DavidsonDepartment of Radiology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Raymond F MuzicDepartment of Radiology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.
Arash KardanDepartment of Radiology, Baylor College of Medicine, Houston, TX, USA. arash.kardan@bcm.edu.ORCID http://orcid.org/0000-0001-6967-1062
University Hospitals of Cleveland · USBaylor College of Medicine · USCase Western Reserve University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleCurrently, the estimated absorbed radiation dose to the lung in

methodsA retrospective analysis was performed on 68 patients who had undergone

resultsPatient-specific lung masses were significantly different from the generic 1 kg when compared individually for each patient (p < 0.0001). Median individualized lung mass was 0.71 (IQR: 0.59, 1.02) kg overall and was significantly different from the generic 1 kg lung mass for female patients [0.59 (0.50, 0.68) kg, (p < 0.0001)] but not for male patients [0.99 (0.71, 1.14) kg, (p = 0.24)]. Median estimated lung absorbed dose was 4.48 (2.38, 11.71) Gy using a patient-specific lung mass and 3.45 (1.81, 6.68) Gy when assuming a 1 kg lung mass for all patients. The estimated lung absorbed dose was significantly different using a patient-specific versus generic 1 kg lung mass when comparing the doses individually for each patient (p < 0.0001). The difference in the estimated lung absorbed dose between the patient-specific and generic 1 kg lung mass method was significant for female patients as a subgroup but not for male patients.

conclusionsThe current method of assuming a 1 kg lung mass for all patients inaccurately estimates the lung absorbed dose in LEVEL OF EVIDENCE: Level 3, Retrospective Study.

Indexed as

Embolization, TherapeuticLiver NeoplasmsFemaleHumansLungMaleMicrospheresRadiometryRetrospective StudiesYttriumYttrium RadioisotopesYttriumYttrium Radioisotopes90Y radioembolizationLung absorbed dosePersonalized dosimetry

Identifiers

PMID35925379
OpenAlexW4289779315

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.