Evidence map›Paper›PMID 35925271›Full record

ReviewInnere Medizin (Heidelberg, Germany)2022

[Targeted treatment of non-small cell lung cancer].

Matthias Scheffler, Sebastian Michels, Lucia Nogova

Abstract readReview
PubMed Publisher
In one paragraph

Review in Innere Medizin (Heidelberg, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matthias SchefflerKlinik I für Innere Medizin, Centrum für Integrierte Onkologie (CIO) Aachen Bonn Köln Düsseldorf, Lung Cancer Group Cologne, Universitätsklinikum Köln (AöR), Kerpener Str. 62, 50937, Köln, Deutschland. matthias.scheffler@uk-koeln.de.
Sebastian MichelsKlinik I für Innere Medizin, Centrum für Integrierte Onkologie (CIO) Aachen Bonn Köln Düsseldorf, Lung Cancer Group Cologne, Universitätsklinikum Köln (AöR), Kerpener Str. 62, 50937, Köln, Deutschland.
Lucia NogovaKlinik I für Innere Medizin, Centrum für Integrierte Onkologie (CIO) Aachen Bonn Köln Düsseldorf, Lung Cancer Group Cologne, Universitätsklinikum Köln (AöR), Kerpener Str. 62, 50937, Köln, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-small cell lung cancer (NSCLC) has made a remarkable development in recent decades with respect to its perception. In the late 1990s it was the "problem child" as the main cause of cancer with increasing tendencies, especially in women and with a pronounced stigmatization. It is now the role model as a biologically rational targeted treatment based on molecular dependencies of the tumor with a vast improvement of the traditionally poor survival times. Molecular tumor boards have long followed the NSCLC example in the assessment of targeted treatment approaches for other tumor entities. This review article gives an overview of the current possibilities for targeted treatment of NSCLC, which nowadays are applicable for nearly one third of all patients with NSCLC.

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsFemaleHumansDrug resistance, neoplasmMolecular genetic analysisMutation/BRAFMutation/EGFRMutation/KRAS

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.