Evidence map›Paper›PMID 35924977›Full record

ArticleGenetics2022

Multitrait Bayesian shrinkage and variable selection models with the BGLR-R package.

Paulino Pérez-Rodríguez, Gustavo de Los Campos

Abstract read
In one paragraph

Article in Genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Mining QTLs and candidate genes in bread wheat associated with kernel hardness through GWAS.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  14. A major QTL region associated with powdery mildew resistance in leaves and fruits of the reconstructed garden strawberry.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Paulino Pérez-RodríguezColegio de Postgraduados, Montecillo, Estado de México 56230, Mexico.ORCID 0000-0002-3202-1784
Gustavo de Los CamposDepartment of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0001-5692-7129

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The BGLR-R package implements various types of single-trait shrinkage/variable selection Bayesian regressions. The package was first released in 2014, since then it has become a software very often used in genomic studies. We recently develop functionality for multitrait models. The implementation allows users to include an arbitrary number of random-effects terms. For each set of predictors, users can choose diffuse, Gaussian, and Gaussian-spike-slab multivariate priors. Unlike other software packages for multitrait genomic regressions, BGLR offers many specifications for (co)variance parameters (unstructured, diagonal, factor analytic, and recursive). Samples from the posterior distribution of the models implemented in the multitrait function are generated using a Gibbs sampler, which is implemented by combining code written in the R and C programming languages. In this article, we provide an overview of the models and methods implemented BGLR's multitrait function, present examples that illustrate the use of the package, and benchmark the performance of the software.

Indexed as

AlgorithmsGenomeBayes TheoremGenomicsGenotypeModels, GeneticBayesianGenomic Predictiongenomic regressionsGenPredGibbs samplinghigh-dimensional regressionmultitrait modelsmultivariate modelspedigree regressionsShared Data Resource

Identifiers

PMID35924977
PMCPMC9434216

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.