Evidence map›Paper›PMID 35924883›Full record

ArticleChembiochem : a European journal of chemical biology2022

Ruthenium(II) Polypyridyl Complexes Containing Simple Dioxo Ligands: a Structure-Activity Relationship Study Shows the Importance of the Charge.

Albert Gandioso, Alessio Vidal, Pierre Burckel, Gilles Gasser, Enzo Alessio

Open access · hybridAbstract read
PubMed Publisher
In one paragraph

Article in Chembiochem : a European journal of chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Albert GandiosoChimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005, Paris, France.
Alessio VidalDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, 34127, Trieste, Italy.
Pierre BurckelUniversité de Paris, Institut de physique du globe de Paris, CNRS, 75005, Paris, France.
Gilles GasserChimie ParisTech, PSL University, CNRS, Institute of Chemistry for Life and Health Sciences, Laboratory for Inorganic Chemical Biology, 75005, Paris, France.
Enzo AlessioDepartment of Chemical and Pharmaceutical Sciences, University of Trieste, 34127, Trieste, Italy.ORCID 0000-0002-4908-9400
Centre National de la Recherche Scientifique · FRUniversity of Trieste · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is one of the main causes of death worldwide. Platinum complexes (i. e., cisplatin, carboplatin, and others) are currently heavily used for the treatment of different types of cancer, but unwanted effects occur. Ruthenium complexes have been shown to be potential promising alternatives to these metal-based drugs. In this work, we performed a structure-activity relationship (SAR) study on two small series of Ru(II) polypyridyl complexes of the type [Ru(L1)

Indexed as

Antineoplastic AgentsCoordination ComplexesNeoplasmsRutheniumCarboplatinCisplatinHumansLigandsMalonatesOxalatesPlatinumStructure-Activity RelationshipAntineoplastic AgentsCarboplatinCisplatinCoordination ComplexesLigandsMalonatesOxalatesPlatinumRutheniumbioinorganic chemistrycancermedicinal inorganic chemistrypolypyridyl complexesruthenium

Identifiers

PMID35924883
OpenAlexW4289836600

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.