Evidence map›Paper›PMID 35924851›Full record

ArticlemBio2022

Mucosal Immune Profiles Associated with Diarrheal Disease Severity in

Amanda D Buskirk, Esther Ndungo, Avital A Shimanovich, Diana Lam, William C Blackwelder, Usman N Ikumapayi, Bing Ma, Helen Powell, Martin Antonio, James P Nataro and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Nutrients · 2025
    Article
  7. Safety and Tolerability of ShigActive™, aAntibiotics (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Amanda D Buskirk *Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Esther Ndungo *Center for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0002-9975-7032
Avital A ShimanovichDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Diana LamCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
William C BlackwelderCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Usman N IkumapayiVaccines and Immunity Theme, Medical Research Council Unit The Gambia, Banjul, The Gambia.
Bing MaDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Helen PowellDepartment of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Martin AntonioVaccines and Immunity Theme, Medical Research Council Unit The Gambia, Banjul, The Gambia.
James P NataroUniversity of Virginiagrid.27755.32 School of Medicine, Department of Pediatrics, Charlottesville, Virginia, USA.
James B KaperDepartment of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Marcela F PasettiCenter for Vaccine Development, University of Maryland School of Medicine, Baltimore, Maryland, USA.ORCID 0000-0003-0894-4009
University of Maryland, Baltimore · USMRC Unit the Gambia · GMUniversity of Virginia · USUniversity of Warwick · GB

Funding

Severe Enteric Disease: Pathogenesis and ResponseU19AI090873 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI BOWER, DONNA ADAMS · 2010 to 2014
$7.2M
Research Training in Gastroenterology and HepatologyT32DK067872 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI RAUFMAN, JEAN-PIERRE · 2005 to 2024
$7.2M
Serological assays to predict Shigella vaccine efficacyR01AI125841 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PASETTI, MARCELA F · 2016 to 2020
$2.8M
Vaccines and maternally acquired immunity to prevent shigellosis in childrenR01AI117734 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI PASETTI, MARCELA F · 2015 to 2019
$2.0M
NIAID NIH HHS R01 AI117734NIAID NIH HHS R01 AI125841NIAID NIH HHS U19 AI090873NIDDK NIH HHS T32 DK067872
6 · The paper itself

Abstract

Enteropathogenic Escherichia coli (EPEC) and

Indexed as

DysenteryEnteropathogenic Escherichia coliEscherichia coli InfectionsShigellaDiarrheaHumansSeverity of Illness IndexVascular Endothelial Growth Factor AVascular Endothelial Growth Factor AEPECGEMSmucosal immune profilesShigella

Identifiers

PMID35924851
PMCPMC9426439
OpenAlexW4289774627

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.