ArticleJournal of clinical periodontology2022
Lack of attention to sex and gender in periodontitis-related randomized clinical trials: A meta-research study.
Article in Journal of clinical periodontology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Effectiveness of two supportive periodontal care protocols and outcome predictors during periodontitis: A randomized controlled trial.Journal of periodontology · 2026Trial
- Association of Interleukin 1 Receptor Antagonist (International journal of molecular sciences · 2026Article
- The male default prevails in biomedical research: sex inclusion in Nature (2025).Biology of sex differences · 2026Article
- Periodontal Status and Gingival Crevicular FluidJournal of clinical medicine · 2025Article
- Knowledge, Attitudes, and Practices to Periodontal Health of the Northeast Chinese Public: Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- Sex and gender differences in periodontal disease: a cross-sectional study in Switzerland.BMC oral health · 2025Observational
- Identification of key genes in periodontitis.Frontiers in genetics · 2025Article
- Gender-specific treatment effects and outcomes reported in orthodontic research. A cross-sectional empirical study.European journal of orthodontics · 2024Article
- Relationship between serum uric acid levels and periodontitis-A cross-sectional study.PloS one · 2024Article
- Association between blood lead and periodontitis among American adults: a cross-sectional study of the national health and nutrition examination survey.Frontiers in pharmacology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
aimThis meta-research study aimed to investigate the level of compliance with the Sex and Gender Equity in Research (SAGER) Guidelines for the inclusion, analysis, and reporting of sex/gender, in periodontitis-related randomized controlled trials (RCTs). MATERIALS AND
methodsFollowing the inclusion of RCTs related to the treatment of periodontitis published between 2018 and 2019, we applied the SAGER checklist to assess the adherence to sex/gender reporting guidelines. We used non-parametric descriptive statistics and correlation models to test the association of the dependent outcome with other variables.
resultsOne hundred and one articles were included in the analysis. The female enrolment ranged between 30% and 94%. Twenty-six studies enrolled less than 50% of female participants. The overall SAGER score (OSS) of item fulfilment ranged between 0 and 7 items with an average of 1.9 items signifying poor guideline adherence to the SAGER guidelines. These findings were not associated with the corresponding author gender (p = .623), publication year (p = .947), and funding source (p = .133). However, a significant but negative correlation with journal impact factor (r = -0.253, p = .026) was observed.
conclusionsSex and gender were frequently disregarded in clinical trial reporting. This oversight might limit the understanding of sex/gender differences in periodontitis-related clinical trials.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.