Evidence map›Paper›PMID 35924678›Full record

ReviewExpert review of vaccines2022

Vaccines against SARS-CoV-2 variants and future pandemics.

Taeyoung Park, Hyogyeong Hwang, Suhyeong Moon, Sang Gu Kang, Seunghyup Song, Young Hun Kim, Hanbi Kim, Eun-Ju Ko, Soon-Do Yoon, Sang-Moo Kang and 1 more

Abstract readReview
In one paragraph

Review in Expert review of vaccines, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Trial
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  12. A cardiotoxicity-eliminated ACE2 variant as a pan-inhibitor against coronavirus cell invasion.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Taeyoung ParkDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.
Hyogyeong HwangDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.
Suhyeong MoonDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.
Sang Gu KangDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.
Seunghyup SongDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.
Young Hun KimDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.
Hanbi KimDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.
Eun-Ju KoCollege of Veterinary Medicine and Interdisciplinary Graduate Program in Advanced Convergence Technology and Science, Jeju National University, Jeju, South Korea.ORCID 0000-0002-1081-904X
Soon-Do YoonDepartment of Chemical and Biomolecular Engineering, Chonnam National University, Yeosu, South Korea.
Sang-Moo KangCenter for Inflammation, Immunity & Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA, USA.
Hye Suk HwangDepartment of Biology, College of Life Science and Industry, Sunchon National University (SCNU), Suncheon, South Korea.

Funding

Influenza vaccines inducing broadly cross protective immunityR01AI093772 · NIAID · GEORGIA STATE UNIVERSITY · PI KANG, SANG-MOO · 2011 to 2020
$4.2M
Seasonal and universal Vaccination in aged populations with pre-existing immunityR01AI154656 · NIAID · GEORGIA STATE UNIVERSITY · PI KANG, SANG-MOO · 2021 to 2025
$2.7M
NIAID NIH HHS R01 AI093772NIAID NIH HHS R01 AI154656
6 · The paper itself

Abstract

introductionVaccination continues to be the most effective method for controlling COVID-19 infectious diseases. Nonetheless, SARS-CoV-2 variants continue to evolve and emerge, resulting in significant public concerns worldwide, even after more than 2 years since the COVID-19 pandemic. It is important to better understand how different COVID-19 vaccine platforms work, why SARS-CoV-2 variants continue to emerge, and what options for improving COVID-19 vaccines can be considered to fight against SARS-CoV-2 variants and future pandemics. AREA COVERED: Here, we reviewed the innate immune sensors in the recognition of SARS-CoV-2 virus, innate and adaptive immunity including neutralizing antibodies by different COVID-19 vaccines. Efficacy comparison of the several COVID-19 vaccine platforms approved for use in humans, concerns about SARS-CoV-2 variants and breakthrough infections, and the options for developing future COIVD-19 vaccines were also covered. EXPERT OPINION: Owing to the continuous emergence of novel pathogens and the reemergence of variants, safer and more effective new vaccines are needed. This review also aims to provide the knowledge basis for the development of next-generation COVID-19 and pan-coronavirus vaccines to provide cross-protection against new SARS-CoV-2 variants and future coronavirus pandemics.

Indexed as

COVID-19Viral VaccinesAntibodies, NeutralizingCOVID-19 VaccinesHumansPandemicsSARS-CoV-2Antibodies, NeutralizingCOVID-19 VaccinesViral Vaccinesnucleic-acid-based vaccineSARS-CoV-2: ACE-2TMPRSS-2universal vaccine

Identifiers

PMID35924678
PMCPMC9979704

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.