Evidence map›Paper›PMID 35924646›Full record

ReviewEFORT open reviews2022

Early-onset scoliosis: a narrative review.

Geovanny Ruiz, Norberto J Torres-Lugo, Pablo Marrero-Ortiz, Humberto Guzmán, Gerardo Olivella, Norman Ramírez

2 registry-linked trialsAbstract readReview
In one paragraph

Review in EFORT open reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06301984 phase3not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Safety and Efficacy Evaluation of Insight GS Growing System in the Surgical Treatment of Early Onset Scoliosis (EOS)

TypeinterventionalSponsorEVEREST PESQUISA E DESENVOLVIMENTO LTDARan2024 to 2027Enrolled26ConditionsEarly Onset Scoliosis (EOS)ArmsInsight GS
NCT06315933 recruitingnot on this map

Long-term Effect of General Anesthesia Before School Age on Neurodevelopment in Children With Congenital Scoliosis

TypeobservationalSponsorPeking Union Medical College HospitalRan2020 to 2026Enrolled150ConditionsGeneral Anesthetics ToxicityArmsGeneral anesthesia
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Deep learning based vertebra localization and Cobb angle estimation using x-ray images.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  5. Continuous distraction with the one-way self-expanding rod promotes vertebral remodelling and stimulates spinal growth in early onset scoliosis: a prospective clinical trial.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Geovanny RuizPonce Health Sciences University, School of Medicine, Ponce, Puerto Rico.
Norberto J Torres-LugoDepartment of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.ORCID 0000-0002-4573-0766
Pablo Marrero-OrtizDepartment of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
Humberto GuzmánDepartment of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.
Gerardo OlivellaDepartment of Orthopaedic Surgery, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico.ORCID 0000-0003-4792-4625
Norman RamírezDepartment of Orthopaedic Surgery, Mayagüez Medical Center, Mayagüez, Puerto Rico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Early-onset scoliosis (EOS) is defined as any spinal deformity that is present before 10 years old, regardless of etiology. Deformity must be evaluated based on the intercorrelation between the lungs, spine, and thorax. Curvatures of early-onset have increased risk of progression, cardiorespiratory problems, and increased morbidity and mortality. Progression of the deformity may produce thoracic insufficiency syndrome, where a distorted thorax is unable to support normal respiratory function or lung growth. Management and treatment of EOS should pursue a holistic approach in which the psychological impact and quality of life of the patient are also taken into consideration. Growth-friendly surgical techniques have not met the initial expectations of correcting scoliotic deformity, promoting thoracic growth, and improving pulmonary function.

Indexed as

complicationsearly-onset scoliosisgrowth-friendly surgeryoutcomesquality of lifethoracic insufficiency syndrome

Identifiers

PMID35924646
PMCPMC9458941

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.