Evidence map›Paper›PMID 35924347›Full record

ArticlePhysiological reports2022

The moderate-intensity continuous exercise maintains renal blood flow and does not impair the renal function.

Shotaro Kawakami, Tetsuhiko Yasuno, Saki Kawakami, Ai Ito, Kanta Fujimi, Takuro Matsuda, Shihoko Nakashima, Kosuke Masutani, Yoshinari Uehara, Yasuki Higaki and 1 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Shotaro KawakamiGraduate School of Sports and Health Science, Fukuoka University, Fukuoka, Japan.ORCID 0000-0002-1334-1918
Tetsuhiko YasunoDivision of Nephrology and Rheumatology, Department of Internal Medicine, Fukuoka University School of Medicine, Fukuoka, Japan.
Saki KawakamiThe Fukuoka University Institute for Physical Activity, Fukuoka, Japan.
Ai ItoThe Fukuoka University Institute for Physical Activity, Fukuoka, Japan.
Kanta FujimiDepartment of Rehabilitation, Fukuoka University Hospital, Fukuoka, Japan.
Takuro MatsudaDepartment of Rehabilitation, Fukuoka University Hospital, Fukuoka, Japan.
Shihoko NakashimaFaculty of Sports and Health Science, Fukuoka University, Fukuoka, Japan.
Kosuke MasutaniDivision of Nephrology and Rheumatology, Department of Internal Medicine, Fukuoka University School of Medicine, Fukuoka, Japan.
Yoshinari UeharaFaculty of Sports and Health Science, Fukuoka University, Fukuoka, Japan.
Yasuki HigakiFaculty of Sports and Health Science, Fukuoka University, Fukuoka, Japan.
Ryoma MichishitaFaculty of Sports and Health Science, Fukuoka University, Fukuoka, Japan.ORCID 0000-0003-4978-1592
Fukuoka Institute of Technology · JPFukuoka University · JPFukuoka University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exercise is restricted for individuals with reduced renal function because exercising reduces blood flow to the kidneys. Safe and effective exercise programs for individuals with reduced renal function have not yet been developed. We previously examined the relationship between exercise intensity and renal blood flow (RBF), revealing that moderate-intensity exercise did not reduce RBF. Determining the effects of exercise duration on RBF may have valuable clinical applications. The current study examined the effects of a single bout of continuous exercise at lactate threshold (LT) intensity on renal hemodynamics. Eight adult males participated in this study. Participants underwent 30 min of aerobic exercise at LT intensity using a cycle ergometer. Evaluation of renal hemodynamics was performed before and after exercise, in the recovery phase using ultrasound echo. Furthermore, blood and urine samplings were conducted before and after exercise, in the recovery phase. Compared with resting, RBF was not significantly changed immediately after continuous exercise (319 ± 102 vs. 308 ± 79 ml/min; p = 0.976) and exhibited no significant changes in the recovery phase. Moreover, urinary kidney injury molecule-1 (uKIM-1) level exhibited no significant change immediately after continuous exercise (0.52 ± 0.20 vs. 0.46 ± 0.27 μg/g creatinine; p = 0.447). In addition, the results revealed no significant change in urinary uKIM-1 in 60-min after exercise. Other renal injury biomarkers exhibited a similar pattern. These findings indicate that a single bout of moderate-intensity continuous exercise maintains RBF and does not induce renal injury.

Indexed as

ExerciseRenal CirculationAdultCreatinineHemodynamicsHumansKidneyMaleCreatininemoderate-intensity continuous exerciserenal functionrenal hemodynamicsrenal injury

Identifiers

PMID35924347
PMCPMC9350468
OpenAlexW4289745784

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.