ArticleFrontiers in neuroscience2022
The Metabolic Syndrome Is Associated With Lower Cognitive Performance and Reduced White Matter Integrity in Midlife: The CARDIA Study.
Article in Frontiers in neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Not All Stroop-Type Tasks Are Alike: Assessing the Impact of Stimulus Material, Task Design, and Cognitive Demand via Meta-analyses Across Neuroimaging Studies.Neuropsychology review · 2025Pooled it
- Comprehensive social determinants of health and brain health in midlife.The journal of prevention of Alzheimer's disease · 2026Article
- Metabolic syndrome is associated with accelerated brain aging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Association of glymphatic function with 40-Hz neural oscillations, systemic metabolic markers, and cognitive performance in healthy aging adults: An EEG and MRI study.Translational psychiatry · 2026Article
- Metabolic syndrome and risk of dementia and cognitive decline: a systematic review and meta-analysis of prospective cohort studies from 6,753,197 participants.GeroScience · 2025Review
- Health insurance coverage moderates the relationship between metabolic syndrome and baseline memory outcomes in Latino older adults.The Clinical neuropsychologist · 2025Article
- White matter microstructural damage and its effect on cognitive impairment in patients with metabolic syndrome and cerebral small vessel disease.Frontiers in neurology · 2025Article
- Longitudinal Association of Changes in Metabolic Syndrome with Cognitive Function: 12-Year Follow-up of the Guangzhou Biobank Cohort Study.Diabetes & metabolism journal · 2025Article
- Better cardiovascular health is associated with slowed clinical progression in autosomal dominant frontotemporal lobar degeneration variant carriers.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome - results from a six-month, double-blind, randomized controlled trial.The American journal of clinical nutrition · 2024Article
- Associations of Polycystic Ovary Syndrome With Indicators of Brain Health at Midlife in the CARDIA Cohort.Neurology · 2024Article
- Metabolic syndrome and cognitive deficits in the Greek cohort of Epirus Health Study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Associations of metabolic syndrome, its severity with cognitive impairment among hemodialysis patients.Diabetology & metabolic syndrome · 2023Article
- Cardiometabolic disease, cognitive decline, and brain structure in middle and older age.Alzheimer's & dementia (Amsterdam, Netherlands)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
Background: Cardiovascular disease risk factors play a critical role in brain aging. The metabolic syndrome (MetS), a constellation of cardiovascular risk factors, has been associated with poorer cognition in old age; however, it is unclear if it is connected to brain health earlier in life. Methods: We investigated the association of MetS ( Results: Participants with MetS had worse performance on tests of verbal fluency, processing speed, executive function, and verbal memory ( Conclusions: MetS is associated with lower cognition and microstructural brain alterations already at midlife, suggesting that MetS should be targeted earlier in life in order to prevent adverse brain and cognitive outcomes.
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