Evidence map›Paper›PMID 35924047›Full record

ArticleFrontiers in pharmacology2022

Model-Informed Drug Development of New Cefoperazone Sodium and Sulbactam Sodium Combination (3:1): Pharmacokinetic/Pharmacodynamic Analysis and Antibacterial Efficacy Against Enterobacteriaceae.

Xi-Wei Ji, Xiao Zhu, Yun Li, Feng Xue, Isabelle Hui San Kuan, Qing-Feng He, Xiang-Rui Meng, Xiao-Qiang Xiang, Yi-Min Cui, Bo Zheng

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 3 countries.

Xi-Wei JiInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Xiao ZhuDepartment of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, China.
Yun LiInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Feng XueInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Isabelle Hui San KuanCertara, Princeton, NJ, United States.
Qing-Feng HeDepartment of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, China.
Xiang-Rui MengIntensive Care Unit, Xiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, China.
Xiao-Qiang XiangDepartment of Clinical Pharmacy and Pharmacy Administration, School of Pharmacy, Fudan University, Shanghai, China.
Yi-Min CuiInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Bo ZhengInstitute of Clinical Pharmacology, Peking University First Hospital, Beijing, China.
Peking University · CNFudan University · CNMonash University · AUPeking University First Hospital · CNXiyuan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cefoperazone/sulbactamenterobacteriaceaeESBLsmodel-informed drug developmentMonte Carlo simulationPK/PD analysis

Identifiers

PMID35924047
PMCPMC9340253
OpenAlexW4285729175

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.