Evidence map›Paper›PMID 35923858›Full record

ArticlePhysical review. X

Emergence of Irregular Activity in Networks of Strongly Coupled Conductance-Based Neurons.

A Sanzeni, M H Histed, N Brunel

Abstract read
In one paragraph

Article in Physical review. X. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. A Python toolbox for neural circuit parameter inference.NPJ systems biology and applications · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Firing rate distributions in plastic networks of spiking neurons.Network neuroscience (Cambridge, Mass.) · 2025
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The Mean Field Approach for Populations of Spiking Neurons.Advances in experimental medicine and biology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

A SanzeniCenter for Theoretical Neuroscience, Columbia University, New York, New York, USA.ORCID 0000-0001-8758-1810
M H HistedNational Institute of Mental Health Intramural Program, NIH, Bethesda, Maryland, USA.ORCID 0000-0001-8235-7908
N BrunelDepartment of Neurobiology, Duke University, Durham, North Carolina, USA.ORCID 0000-0002-2272-3248

Funding

Computation by recurrent circuits of the cerebral cortexZIAMH002967 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI HISTED, MARK · 2017 to 2025
$7.0M
Circuitry underlying response summation in mouse and primate: Theory and experimentU01NS108683 · NINDS · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI BRUNEL, NICOLAS, MILLER, KENNETH D · 2018 to 2020
$2.8M
Intramural NIH HHS ZIA MH002967NINDS NIH HHS U01 NS108683
6 · The paper itself

Abstract

Cortical neurons are characterized by irregular firing and a broad distribution of rates. The balanced state model explains these observations with a cancellation of mean excitatory and inhibitory currents, which makes fluctuations drive firing. In networks of neurons with current-based synapses, the balanced state emerges dynamically if coupling is strong, i.e., if the mean number of synapses per neuron

Indexed as

Biological PhysicsComplex SystemsInterdisciplinary Physics

Identifiers

PMID35923858
PMCPMC9344604

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.