Evidence map›Paper›PMID 35923721›Full record

ArticleRSC medicinal chemistry2022

Pegylated-polycaprolactone nano-sized drug delivery platforms loaded with biocompatible silver(i) complexes for anticancer therapeutics.

Despoina Varna, Evi Christodoulou, Eleni Gounari, Chrysanthi Pinelopi Apostolidou, Georgios Landrou, Rigini Papi, George Koliakos, Athanassios G Coutsolelos, Dimitrios N Bikiaris, Panagiotis A Angaridis

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Despoina VarnaAristotle University of Thessaloniki, Department of Chemistry, University Campus 54124 Thessaloniki Greece dbic@chem.auth.gr panosangaridis@chem.auth.gr.
Evi ChristodoulouAristotle University of Thessaloniki, Department of Chemistry, University Campus 54124 Thessaloniki Greece dbic@chem.auth.gr panosangaridis@chem.auth.gr.
Eleni GounariBiohellenika Biotechnology Company Leoforos Georgikis Scholis 65 57001 Thessaloniki Greece.
Chrysanthi Pinelopi ApostolidouDepartment of Materials Science and Technology and Institute of Electronic Structure and Laser (I.E.S.L.), Foundation for Research and Technology - Hellas (FO.R.T.H.), University of Crete Vassilika Vouton 70013 Heraklion Greece.
Georgios LandrouDepartment of Chemistry, Voutes Campus, University of Crete 70013 Heraklion Greece.
Rigini PapiAristotle University of Thessaloniki, Department of Chemistry, University Campus 54124 Thessaloniki Greece dbic@chem.auth.gr panosangaridis@chem.auth.gr.
George KoliakosBiohellenika Biotechnology Company Leoforos Georgikis Scholis 65 57001 Thessaloniki Greece.
Athanassios G CoutsolelosDepartment of Chemistry, Voutes Campus, University of Crete 70013 Heraklion Greece.ORCID https://orcid.org/0000-0001-5682-2968
Dimitrios N BikiarisAristotle University of Thessaloniki, Department of Chemistry, University Campus 54124 Thessaloniki Greece dbic@chem.auth.gr panosangaridis@chem.auth.gr.ORCID https://orcid.org/0000-0001-8458-4952
Panagiotis A AngaridisAristotle University of Thessaloniki, Department of Chemistry, University Campus 54124 Thessaloniki Greece dbic@chem.auth.gr panosangaridis@chem.auth.gr.ORCID https://orcid.org/0000-0002-1733-9225

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cytotoxic potential of Ag(i) coordination compounds against cancer cells is widely recognized, but their frequently low water solubility and potential adverse interactions of Ag(i) ions in biological media require their incorporation into suitable platforms to ensure effective transport and delivery at target sites. Herein, we developed and evaluated the

Identifiers

PMID35923721
PMCPMC9298185

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.