ArticleClinical, cosmetic and investigational dentistry2022
Recurrent Aphthous Stomatitis Affects Quality of Life. A Case-Control Study.
Article in Clinical, cosmetic and investigational dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 6 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Psychological factors and quality of life in oral mucosal diseases: A systematic review of assessment tools and clinical implications.BMC oral health · 2026Pooled it
- Mucoadhesive Drug Delivery Systems for Oral Chronic Inflammatory Mucosal Diseases. The Future is Already Present. A Systematic Review.Oral diseases · 2026Pooled it
- Laser therapy versus placebo treatment for aphthous ulcers: a systematic review and meta‑analysis.Lasers in medical science · 2025Pooled it
- Effectiveness of low-level laser therapy in reducing pain score and healing time of recurrent aphthous stomatitis: a systematic review and meta-analysis.Systematic reviews · 2024Pooled it
- The relationship between Helicobacter pylori infection and recurrent aphthous stomatitis: a systematic review and meta-analysis.Clinical oral investigations · 2023Pooled it
- Vitamin D deficiency and risk of recurrent aphthous stomatitis: updated meta-analysis with trial sequential analysis.Frontiers in nutrition · 2023Pooled it
- A comparative study of the efficacy of apitoxin gel versus photobiomodulation by diode laser for recurrent aphthous stomatitis treatment.Journal of Taibah University Medical Sciences · 2026Article
- Solubility-Enhanced α‑Mangostin Bilayer Films: Synergizing Mucoadhesion and Protection for Effective Aphthous Ulcer Treatment.ACS omega · 2026Article
- Interrelationships Among Psychological Conditions, Oral Health-related Quality of Life, and Clinical Characteristics in Chinese Patients with Minor Recurrent Aphthous Stomatitis.International dental journal · 2026Article
- The impact of oral diseases on the quality of life of patients attending the oral medicine clinic at a dental specialty centre.Scientific reports · 2026Article
- Salivary proteomics suggests persistent inflammatory signatures after clinical healing in recurrent aphthous stomatitis: a hypothesis-generating case-control study.BMC oral health · 2026Article
- Prevalence profile perceived stress and impact on quality of life for recurrent aphthous ulcers: a cross-sectional epidemiological study in Egypt.BMC oral health · 2026Article
- Prevalence, risk factors, and psychosocial impact of self-reported recurrent oral ulceration among Palestinian medical and dental students: a multicenter cross-sectional study.BMC oral health · 2026Article
- Association Between Parents' Self-Perceived Oral Health Knowledge and the Presence of Dental Caries in Their Children.Clinics and practice · 2025Article
- A Topical Combination of Xyloglucan and Pea Protein Effectively Manages Oral Ulcers In Vivo.Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology · 2025Article
- Assessing the Impact of Recurrent Aphthous Ulcer on Oral Health-Related Quality of Life.Journal of pharmacy & bioallied sciences · 2025Article
- Recurrent aphthous stomatitis (RAS) and its related factors among the Azar cohort population.BMC oral health · 2025Article
- Oral Health-Related Quality of Life in Patients Rehabilitated with Dental Implants.Healthcare (Basel, Switzerland) · 2025Article
- In Situ Gelling Dexamethasone Oromucosal Formulation: Physical Characteristics Influencing Drug Delivery.Gels (Basel, Switzerland) · 2025Article
- Age-related variations in mental health and wellbeing during the first wave of the COVID-19 pandemic: a multi-country survey analysis.Frontiers in public health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aim: To determine the impact of recurrent aphthous stomatitis on quality of life related to oral health, and then to determine the relationship between the observed impact and lesions characteristics. Methods: In this prospective case-control study (n=62), patients were divided into a healthy group (people with no history of ulcers) and recurrent aphthous stomatitis (people who had an active ulcer at study entry). The latter were also evaluated when the lesion disappeared (remission stage). We record the quality of life in all groups using the impact profile of oral health in its abbreviated Spanish version (OHIP-14SP). Finally, we correlate the clinical characteristics of the lesions with the levels of quality of life. Results: All the lesions were of the minor morphological type. Most of the lesions were located on the lining mucosa, primarily on the lips. Patients report a lower quality of life during ulcer episodes compared to ulcer-free periods, and this impact is positively related to the number and size of lesions. Conclusion: We concluded that recurrent aphthous stomatitis increased the negative effects of oral health on the quality of life of patients. The number and size of ulcers are responsible for this impact. Our results suggest that, if intervened locally, general relief of the condition could be achieved.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.