Evidence map›Paper›PMID 35923664›Full record

ArticleEnvironmental science: atmospheres2022

Changes to lung surfactant monolayers upon exposure to gas phase ozone observed using X-ray and neutron reflectivity.

Joanna M Hemming, Justyna Szyroka, Gracia Shokano, Thomas Arnold, Maximilian W A Skoda, Adrian R Rennie, Katherine C Thompson

Open access · diamondAbstract read
In one paragraph

Article in Environmental science: atmospheres, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Joanna M HemmingInstitute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London Malet Street London WC1E 7HX UK k.thompson@bbk.ac.uk.
Justyna SzyrokaInstitute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London Malet Street London WC1E 7HX UK k.thompson@bbk.ac.uk.
Gracia ShokanoInstitute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London Malet Street London WC1E 7HX UK k.thompson@bbk.ac.uk.
Thomas ArnoldEuropean Spallation Source The ESS Campus Lund Sweden SE-221 00.ORCID https://orcid.org/0000-0001-8295-3822
Maximilian W A SkodaISIS Neutron and Muon Source, Science and Technology Facilities Council, Rutherford Appleton Laboratory Harwell, Didcot Oxford OX11 0QX UK.ORCID https://orcid.org/0000-0003-0086-2965
Adrian R RennieDepartment of Chemistry - Ångström and Centre for Neutron Scattering, Uppsala University Box 538 75121 Uppsala Sweden.ORCID https://orcid.org/0000-0001-8185-3272
Katherine C ThompsonInstitute of Structural and Molecular Biology, Department of Biological Sciences, Birkbeck, University of London Malet Street London WC1E 7HX UK k.thompson@bbk.ac.uk.ORCID https://orcid.org/0000-0002-9293-610X
Institute of Structural and Molecular Biology · GBRutherford Appleton Laboratory · GBUppsala University · SE

Funding

Wellcome Trust
6 · The paper itself

Abstract

Exposure to the secondary pollutant ozone in ambient air is associated with adverse health effects when inhaled. In this work we use surface pressure measurements, combined with X-ray and neutron reflection, to observe changes in a layer of lung surfactant at the air water interface when exposed to gas phase ozone. The results demonstrate that the layer reacts with ozone changing its physical characteristics. A slight loss of material, a significant thinning of the layer and increased hydration of the surfactant material is observed. The results support the hypothesis that unsaturated lipids present in lung surfactant are still susceptible to rapid reaction with ozone and the reaction changes the properties of the interfacial layer.

Identifiers

PMID35923664
PMCPMC9281625
OpenAlexW4285307502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.