Evidence map›Paper›PMID 35923605›Full record

ArticleSouthern African journal of HIV medicine2022

Tracking adverse drug reactions and medication errors in the Central Chronic Medicine Dispensing and Distribution (CCMDD) programme in South Africa.

Kennedy Otwombe, Maggie Munsamy, Mukesh Dheda, Nishana Ramdas, Corlee Herbst, Merlin Pillay, Tanya van Tonder, Celicia Serenata, Samanta Lalla-Edward

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Southern African journal of HIV medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kennedy OtwombePerinatal HIV Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID 0000-0002-7433-4383
Maggie MunsamyCentral Chronic Medicines Dispensing and Distribution (CCMDD) Programme, National Department of Health, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-0597-5881
Mukesh DhedaPharmacovigilance Programme for Public Health, National Department of Health, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-9355-5405
Nishana RamdasCentral Chronic Medicines Dispensing and Distribution (CCMDD) Programme, National Department of Health, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-9534-2972
Corlee HerbstCentral Chronic Medicines Dispensing and Distribution (CCMDD) Programme, National Department of Health, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-0941-8097
Merlin PillayCentral Chronic Medicines Dispensing and Distribution (CCMDD) Programme, National Department of Health, Pretoria, South Africa.ORCID https://orcid.org/0000-0002-2804-9792
Tanya van TonderOpinion Solutions, Johannesburg, South Africa.ORCID https://orcid.org/0000-0002-5572-8977
Celicia SerenataEzintsha, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0001-7921-0948
Samanta Lalla-EdwardEzintsha, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.ORCID https://orcid.org/0000-0003-3597-1643
National Department of Health · PGUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The South African Central Chronic Medicine Dispensing and Distribution (CCMDD) programme is a National Health Insurance (NHI) initiative that improves access to medicine for patients. Objectives: To describe the frequency of adverse drug reactions (ADRs) and medication errors reported in stable patients living with HIV. Method: This descriptive cross-sectional survey was conducted from August 2020 to October 2020, targeting tenofovir disoproxil fumarate/lamivudine/dolutegravir (TLD) and tenofovir disoproxil fumarate/emtricitabine/efavirenz (TEE) patients. The distribution of ADRs and medication errors is presented. Results: Of 9621 patients, 30.8% ( Conclusion: About one in seven patients reported ADRs under TLD. Medication errors were low, possibly due to effective quality control measures and stable patients being on the programme. Knowing the frequency of ADRs and medication errors is critical for enhancing the CCMDD programme.

Indexed as

ADRsCCMDDHIVMedication errorsNational Health Insurance

Identifiers

PMID35923605
PMCPMC9210172
OpenAlexW4280506559

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.