Evidence map›Paper›PMID 35923508›Full record

ArticleJournal of obstetrics and gynaecology of India2022

Consanguineous Marriage and Early Pregnancy Loss in Rural to Peri-Urban India.

Jamie M Robertson, Kalpana Basany, Fouzia Farooq, Xiaoqing Tan, Gong Tang, Clareann H Bunker, P S Reddy, Catherine L Haggerty

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of obstetrics and gynaecology of India, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Jamie M RobertsonDepartment of Epidemiology, University of Pittsburgh, 130 Desoto Street, Pittsburgh, PA 15261 USA.
Kalpana BasanySHARE INDIA, MediCiti Institute of Medical Sciences, Ghanpur, Telangana State 501401 India.
Fouzia FarooqDepartment of Epidemiology, University of Pittsburgh, 130 Desoto Street, Pittsburgh, PA 15261 USA.
Xiaoqing TanDepartment of Biostatistics, University of Pittsburgh, 130 Desoto Street, Pittsburgh, PA 15261 USA.
Gong TangDepartment of Biostatistics, University of Pittsburgh, 130 Desoto Street, Pittsburgh, PA 15261 USA.
Clareann H BunkerDepartment of Epidemiology, University of Pittsburgh, 130 Desoto Street, Pittsburgh, PA 15261 USA.
P S ReddySHARE INDIA, MediCiti Institute of Medical Sciences, Ghanpur, Telangana State 501401 India.
Catherine L HaggertyDepartment of Epidemiology, University of Pittsburgh, 130 Desoto Street, Pittsburgh, PA 15261 USA.ORCID 0000-0002-9849-7865
University of Pittsburgh · USBrigham and Women's Hospital · USMediciti Institute of Medical Sciences · IN

Funding

Cardiovascular Epidemiology Training ProgramT32HL083825 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI AKIRA SEKIKAWA · 2008 to 2026
$6.1M
SHARE India University Pittsburgh Population and Intervention Research TrainingD43TW009078 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BUNKER, CLAREANN H. · 2011 to 2015
$1.0M
FIC NIH HHS D43 TW009078NHLBI NIH HHS T32 HL083825
6 · The paper itself

Abstract

Background: Consanguineous marriage (CM) has been linked to spontaneous abortion (SAB), although studies have largely been cross-sectional and likely underestimated early loss. We aimed to determine the relationships between CM and SAB in a prospective pregnancy cohort study in Telangana State, India. Methods: Data from 661 participants aged 15-35 years in the Longitudinal Indian Family hEalth (LIFE) study actively followed for pregnancy and pregnancy loss were analyzed. SAB was classified as early (< 8) or late (8-22) weeks gestation. We used logistic regression to model the relationships between CM, defined by first-cousin marriage, and SAB, adjusted for maternal age. Results: Women in CM were at a modestly increased risk of any (OR Conclusion: Among couples in southern India, there was a modest increase in early but not late SAB among CMs which may be explained by the expected influence of chromosomal abnormalities and lethal homozygous recessive disease on early loss. Pre- and Peri-marital Health Counseling that addresses this risk may be warranted. Supplementary Information: The online version contains supplementary material available at 10.1007/s13224-021-01498-7.

Indexed as

Consanguineous marriageCousin marriageIndiaPregnancy lossSpontaneous abortion

Identifiers

PMID35923508
PMCPMC9339451
OpenAlexW3183852984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.