Evidence map›Paper›PMID 35923426›Full record

ArticleEClinicalMedicine2022

Estimating the burden of hepatitis B virus infection in Laos between 2020 and 2021: A cross-sectional seroprevalence survey.

Philavanh Sitbounlang, Eric Deharo, Vatthanaphone Latthaphasavang, Agnès Marchio, Chanthala Soukhsakhone, Vonephet Soinxay, Mayfong Mayxay, Nicolas Steenkeste, Pascal Vincelot, Stéphane Bertani and 3 more

Open access · goldAbstract read
In one paragraph

Article in EClinicalMedicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 4 countries.

Philavanh SitbounlangCenter Infectiology Lao-Christophe Mérieux (CILM), Ministry of Health, Samsenthai Road, Sisattanak District, Vientiane 3888, Laos.
Eric DeharoInstitut de Recherche pour le Développement, Ban Naxai, Saysettha District, Vientiane 5992, Laos.
Vatthanaphone LatthaphasavangInstitut de Recherche pour le Développement, Ban Naxai, Saysettha District, Vientiane 5992, Laos.
Agnès MarchioUnité "Organisation Nucléaire et Oncogenèse", INSERM U993, Institut Pasteur, Paris, France.
Chanthala SoukhsakhoneNational Blood Transfusion Center, Lao Red Cross, Phai Nam street, Vientiane, Laos.
Vonephet SoinxayNational Blood Transfusion Center, Lao Red Cross, Phai Nam street, Vientiane, Laos.
Mayfong MayxayMinistry of Health, University of Health Sciences, Vientiane, Laos.
Nicolas SteenkesteFondation Mérieux, Lyon, France.
Pascal VincelotFondation Mérieux, Lyon, France.
Stéphane BertaniIRD, UPS, UMR 152 PHARMADEV, Université de Toulouse, Toulouse, France.
Sysay PalamyFaculty of Pharmacy of Vientiane, University of Health Sciences, Laos.
Phimpha PaboribouneCenter Infectiology Lao-Christophe Mérieux (CILM), Ministry of Health, Samsenthai Road, Sisattanak District, Vientiane 3888, Laos.
Pascal PineauUnité "Organisation Nucléaire et Oncogenèse", INSERM U993, Institut Pasteur, Paris, France.
Fondation Mérieux · FRInserm · FRNational Blood Transfusion Service · NGCentre d’Infectiologie Christophe Mérieux of Laos · LAInternational Potato Center · PEMinistry of Health · LAUniversité Toulouse III - Paul Sabatier · FRUniversity of Health Sciences Vientiane · LA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Laos is considered highly endemic for persistent infection with hepatitis B virus (HBV). To eliminate this burden, it has gradually implemented universal anti-hepatitis B immunisation of newborns over the past two decades. Methods: Using VIKIA® HBsAg, a rapid test for the qualitative detection of the HBV surface antigen, we conducted between Sep 1st, 2020 and Aug 31st, 2021 the largest prospective prevalence survey ever in Laos. This survey included blood donors (BD, Findings: We observed an HBsAg seroprevalence ranging from 2.6% in blood donors to 8.0% in HIV-infected patients. In BD, men were significantly more at risk to be carriers than women (RR = 1.2, Interpretation: We considered that HBsAg prevalence probably ranges between 5.0% and 6.0% of the total population. Thus, we consider that Laos may no longer be highly endemic for chronic HBV infection but rather a country with intermediate endemicity. Funding: The funding sources were the Agence Universitaire de la Francophonie, the French Government, the French Institute for Sustainable Development (IRD), and European Union's Horizon 2020 Marie Sklodowska-Curie Actions (MSCA) - Research and Innovation Staff Exchange - (RISE) under grant agreement N° 823935.

Indexed as

Endemic countryHepatitis B virusLaosSoutheast AsiaUniversal Immunization

Identifiers

PMID35923426
PMCPMC9340506
OpenAlexW4288747419

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.