Identification and Implications of HIV-1 CRF01_AE Subtype in Hawai'i.

Logan S Dean, Ivo N SahBandar, Cecilia M Shikuma

Abstract read

In one paragraph

Article in Hawai'i journal of health & social welfare, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Logan S DeanJohn A. Burns School of Medicine, University of Hawai'i, Honolulu, HI (LSD, INS, CMS).

Ivo N SahBandarWeil Cornell Medicine, New York, NY (INS).

Cecilia M ShikumaJohn A. Burns School of Medicine, University of Hawai'i, Honolulu, HI (LSD, INS, CMS).

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Benjamin C. Fogelgren · 2017 to 2026

$59.5M

Tracking and Evaluation CoreU54GM138062 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI SHIKUMA, CECILIA M. · 2021 to 2025

$15.5M

Transdisciplinary Health Disparities Research Training for Native Hawaiians and Pacific StudentsT37MD008636 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI KAHOLOKULA, JOSEPH KEAWE'AIMOKU, SY, ANGELA U · 2014 to 2025

$2.7M

NIGMS NIH HHS U54 GM138062NIMHD NIH HHS T37 MD008636NIMHD NIH HHS U54 MD007601

6 · The paper itself

Abstract

Human Immunodeficiency Virus has a high propensity for genetic variation, demonstrated by its complex phylogeny and multiplicity of subtypes. Subtype B is predominant in North America as well as in Hawai'i while CRF01_AE is found in over 50% of cases in the Philippines and Southeast Asia. In a small collaborative study between the Hawai'i Center for AIDS and Philippines General Hospital, molecular phylogenetic subtyping was conducted on HIV+ participants. Two of 15 (13%) participants from the Hawai'i cohort and 12 of 21 (57%) participants from the Philippines cohort were identified as having CRF01_AE subtype of HIV-1, with remaining participants identified as subtype B. While one individual in Hawai'i with CRF01_AE had emigrated from the Philippines, the other participant from Hawai'i with CRF01_AE subtype was a local individual, born and raised in Hawai'i. The authors report that HIV subtype diversity may be increased in Hawai'i and discuss its potential clinical and public health implications.

Indexed as

HIV-1HIV InfectionsCohort StudiesHawaiiHumansPhylogenyCRF01_AEHawai‘iHIVPhilippines

Identifiers

PMID35923383

PMCPMC9344534

What OpenQuestion holds

Textmetadata

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.