Evidence map›Paper›PMID 35923339›Full record

ArticleRadiology case reports2022

A case of improved quality of life in a patient with inoperable pancreatic cancer after repeated RFA.

Nino Toria, Nino Kikodze, Nona Janikashvili, Ia Pantsulaia, Malkhaz Mizandari, Tinatin Chikovani, Nagy Habib

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Radiology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Advances in radiofrequency ablation for pancreatic cancer.World journal of gastrointestinal oncology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Nino ToriaDepartment of Immunology, Tbilisi State Medical University, 33 Vazha-Pshavela Ave, Tbilisi, 0186, Georgia.
Nino KikodzeDepartment of Immunology, Tbilisi State Medical University, 33 Vazha-Pshavela Ave, Tbilisi, 0186, Georgia.
Nona JanikashviliDepartment of Immunology, Tbilisi State Medical University, 33 Vazha-Pshavela Ave, Tbilisi, 0186, Georgia.
Ia PantsulaiaDepartment of Immunology, Tbilisi State Medical University, 33 Vazha-Pshavela Ave, Tbilisi, 0186, Georgia.
Malkhaz MizandariDepartment of Interventional Radiology, Tbilisi State Medical University, Tbilisi, Georgia.
Tinatin ChikovaniDepartment of Immunology, Tbilisi State Medical University, 33 Vazha-Pshavela Ave, Tbilisi, 0186, Georgia.
Nagy HabibDepartment of Surgery and Cancer, Hammersmith Hospital, Imperial College London, London, UK.
Tbilisi State Medical University · GEHammersmith Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Radiofrequency ablation (RFA) has widespread popularity due to its immune-modulation effects in many cancers. Optimal settings to apply RFA in pancreatic cancer, in which the advanced stage of the tumor at the diagnosis makes various therapeutic approaches fail, are still demanding. We report the case of a patient with unresectable pancreatic cancer in which 3 repetitive RFA has been applied over a period of 3 months. Results revealed an improvement in the patient's clinical condition associated with the reduced incidence of CD4+CD45RO+ T lymphocytes and declined TGF-β level in serum. The good quality of life and disease-free survival were maintained for the next months. Booster application of RFA procedure might be a promising option to improve the quality of life in pancreatic cancer patients.

Indexed as

CytokinesImmunomodulationPercutaneous radiofrequency ablationT lymphocytesUnresectable pancreatic cancer

Identifiers

PMID35923339
PMCPMC9340145
OpenAlexW4288680462

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.