ArticleDisease markers2022
Reference Intervals of Spot Urine Creatinine-to-Osmolality Ratio as a Surrogate of Urinary Creatinine Excretion Rate.
Article in Disease markers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Employing urinary biomarkers in predicting renal recovery three months after in-hospital acute kidney injury.Renal failure · 2025Article
- Reference intervals for urine creatinine-to-specific gravity ratio as an indicator of relative creatinine excretion rate: a cross-sectional study.Annals of medicine and surgery (2012) · 2025Article
- J-shaped association between blood urea nitrogen-to-creatinine ratio and mortality in critically ill patients with acute pancreatitis: a retrospective cohort study using the MIMIC-IV database.European journal of medical research · 2025Article
- Employing urinary biomarkers to infer the absence of acute kidney disease in outpatients with a single serum creatinine measurement.Renal failure · 2024Article
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2 authors.
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Abstract
A spot urine creatinine-to-osmolality ratio (sUCr/Osm) is proposed as a surrogate of the urinary excretion rate of creatinine (Cr) and convenient for forecasting serum Cr (SCr) trends. The lower the sUCr/Osm, the lower the excreted Cr amount accompanied by per unit of osmoles, the higher the risk of Cr accumulation. For exploring the reference intervals of sUCr/Osm in general adults, a cross-sectional analysis was performed on a subset of data from the National Health and Nutrition Examination Survey (NHANES) 2011-2012. Of the eligible 3,316 adults aged 18.0 to 79.9 years, the age (mean ± SD) was 45.2 ± 17.2 years old, women was 45.02%, body weight (BW) was 76.1 ± 14.5 kg, and African Americans was 23.6%. Blood urea nitrogen (BUN) was 12.6 ± 4.7 mg/dL; SCr was 0.89 ± 0.34 mg/dL. As spot urine Cr and osmolality were 127.1 ± 84.0 mg/dl and 649 ± 266 mOsm/kg, respectively, sUCr/Osm was 0.19 ± 0.08. With adjustment of factors related to personal urinary excretion of Cr and osmoles by multivariable regression analysis, the estimated sUCr/Osm (esUCr/Osm) for an individual was 0.153 × (age in year)
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