ArticleFrontiers in nutrition2022
Association between dried fruit intake and pan-cancers incidence risk: A two-sample Mendelian randomization study.
Article in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Dietary Pattern and Risk of Thyroid Cancer: A Systematic Review.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026Pooled it
- Risk factors for prostate cancer: An umbrella review of prospective observational studies and mendelian randomization analyses.PLoS medicine · 2024Pooled it
- Pooled it
- Causal relationship between diet and common female diseases: a comprehensive Mendelian randomization study.BMC women's health · 2025Article
- Genetically proxied risk and protective factors for pancreatic cancer: a systematic review and meta-analysis of Mendelian randomization studies.Journal of gastrointestinal oncology · 2025Article
- Causal association between dietary factors and telomere length revealed by mendelian randomization.Scientific reports · 2025Article
- Causal associations of MICB, CTSA, and MMP9 proteins with oral cancer: Mendelian randomization study.Scientific reports · 2024Article
- Association between fruit intake and non-small cell lung cancer: a Mendelian randomization study.Translational lung cancer research · 2024Article
- The Risk of Oral Cancer and the High Consumption of Thermally Processed Meat Containing Mutagenic and Carcinogenic Compounds.Nutrients · 2024Article
- Associations between genetically determined dietary factors and risk of autism spectrum disorder: a Mendelian randomization study.Frontiers in nutrition · 2024Article
- Causal association of dietary factors with five common cancers: univariate and multivariate Mendelian randomization studies.Frontiers in nutrition · 2024Article
- Causal relationship between dietary factors and breast cancer risk: A Mendelian randomization study.Heliyon · 2023Article
- Dried Fruits, Nuts, and Cancer Risk and Survival: A Review of the Evidence and Future Research Directions.Nutrients · 2023Review
- Associations between diet and incidence risk of lung cancer: A Mendelian randomization study.Frontiers in nutrition · 2023Article
- Dried fruit intake causally protects against low back pain: A Mendelian randomization study.Frontiers in nutrition · 2023Article
- The causal relationship between abdominal obesity and lower bone mineral density: A two-sample mendelian randomization study.Frontiers in genetics · 2022Article
- The relationship between processed meat, red meat, and risk of types of cancer: A Mendelian randomization study.Frontiers in nutrition · 2022Article
- Circulating micronutrients as protective factors for the retinal structure and vasculature: Mendelian randomization analyses.Advances in ophthalmology practice and researchArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
Background: Observational studies have revealed that dried fruit intake may be associated with cancer incidence; however, confounding factors make the results prone to be disturbed. Therefore, we conducted a two-sample Mendelian randomization (MR) study to explore the causal relationship between dried fruit intake and 11 site-specific cancers. Materials and methods: Forty-three single nucleoside polymers (SNPs) with robust genome-wide association study (GWAS) evidence, strongly correlated with dried fruit intake, were used as instrumental variables (IVs) in this study. The summary-level genetic datasets of site-specific cancers were obtained from the Oncoarray oral cavity and oropharyngeal cancer consortium, International Lung Cancer Consortium, Breast Cancer Association Consortium (BCAC), Ovarian Cancer Association Consortium, PanScan1, and GWAS of other scholars. We analyzed the causality between dried fruit intake and 11 site-specific cancers using the inverse-variance-weighted (IVW) and weighted median (WM) methods. For the results of the MR analysis, Cochran's Results: The evidence from IVW analyses showed that each increase of dried fruit intake by one standard deviation was statistically significantly associated with 82.68% decrease of oral cavity/pharyngeal cancer incidence risk ( Conclusion: The intake of dried fruits may have a protective effect against some site-specific cancers. Therefore, health education and a reasonable adjustment of dietary proportions may help in the primary prevention of cancer.
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