Evidence map›Paper›PMID 35923077›Full record

ArticleJournal of cellular and molecular medicine2022

Antitumor effect and metabonomics of niclosamide micelles.

Jiarong Hang, Yu Chen, Lukuan Liu, Liwen Chen, Jiqin Fang, Fei Wang, Miao Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Antitumor effect and metabonomics of niclosamide micelles.Journal of cellular and molecular medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jiarong HangSchool of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China.
Yu ChenSchool of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China.
Lukuan LiuSchool of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China.
Liwen ChenSchool of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China.
Jiqin FangSchool of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China.
Fei WangFaculty of Robot Science and Engineering, Northeastern University, Shenyang, China.
Miao WangSchool of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang, China.ORCID 0000-0002-1594-603X
Shenyang Pharmaceutical University · CNNortheastern University · CN

Funding

Liaoning Province Science and Technology Administration 2019-ZD-0456National Natural Science Foundation of China 81973284
6 · The paper itself

Abstract

Polymer micelles now have promising applications in the treatment of cancer, increasing the water solubility and bioavailability of drugs. Previous studies have found that micelles of niclosamide have good anti-liver cancer effect. In view of the poor water solubility of niclosamide (NIC), we decided to prepare niclosamide micelles. However, its therapeutic mechanism is not clear, so this paper conducted a preliminary study on its vitro anti-tumour mechanism and metabonomics to find out its impact. It was found that the drug-loaded micelles (PEG

Indexed as

MicellesNiclosamideAnimalsBiomarkersChromatography, LiquidMetabolomicsMiceTandem Mass SpectrometryWaterBiomarkersMicellesNiclosamideWatercytotoxicitymetabonomicsnanomicelleniclosamide

Identifiers

PMID35923077
PMCPMC9465187
OpenAlexW4289731488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.