Evidence map›Paper›PMID 35922961›Full record

Trial reportThe Journal of international medical research2022

Treating peripheral neuropathy in individuals with type 2 diabetes mellitus with intraneural facilitation: a single blind randomized control trial.

Kyan Sahba, Lee Berk, Mark Bussell, Everett Lohman, Francis Zamora, Lida Gharibvand

2 registry-linked trialsOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05165368 nacompletednot on this mapstarted 2023, after this paper: background citation

Effect of Gluten-Free Dietary Education and Intraneural Facilitation® Therapy on Quality of Life in People With Diabetic Neuropathy

TypeinterventionalSponsorLoma Linda UniversityRan2023 to 2025Enrolled46ConditionsDiabetic Neuropathy, Distal Symmetric Polyneuropathy (Manifestation)ArmsIntraneural Facilitation® Therapy (INF® Therapy), INF® Therapy
NCT06663670 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Comparative Effects of Intraneural Facilitation Therapy and Nerve Flossing Technique on Pain, Balance, Gait, and Quality of Life in Patients With Diabetic Peripheral Neuropathy

TypeinterventionalSponsorRiphah International UniversityRan2024 to 2025Enrolled44ConditionsDiabetic Peripheral NeuropathyArmsIntraneural Facilitation Therapy, Nerve Flossing Technique
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kyan SahbaDepartment of Allied Health Studies, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA.ORCID https://orcid.org/0000-0001-8110-3973
Lee BerkDepartment of Allied Health Studies, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA.
Mark BussellNeuropathic Therapy Center, Loma Linda University Health, Loma Linda, CA, USA.
Everett LohmanDepartment of Physical Therapy, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA.
Francis ZamoraDepartment of Allied Health Studies, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA.
Lida GharibvandDepartment of Allied Health Studies, School of Allied Health Professions, Loma Linda University, Loma Linda, CA, USA.
Loma Linda University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effectiveness of intraneural facilitation (INF) for the treatment of diabetic peripheral neuropathy (DPN).

methodsThis single-blind, randomized clinical trial enrolled patients with type 2 diabetes mellitus and moderate-to-severe DPN symptoms below the ankle. Patients were randomly assigned to receive INF or sham treatment. In the INF group, trained INF physical therapists provided therapy for 50-60 min, three times a week for 3 weeks. Sham treatment consisted of patients believing they received anodyne therapy for 3 weeks. Pre- and post-treatment data were compared between the two groups for quality of life, balance, gait, protective sensory function and pain outcome measures.

resultsA total of 28 patients (17 males) were enrolled in the study (INF group

conclusionsINF treatment improved pain perception, the composite static balance score and protective sensations in patients with DPN.Research Registry number: CNCT04025320.

Indexed as

Diabetes Mellitus, Type 2Diabetic NeuropathiesFemaleHumansMalePainQuality of LifeSingle-Blind MethodDiabetesintraneural facilitationneuropathyphysiotherapy

Identifiers

PMID35922961
PMCPMC9358562
OpenAlexW4289732172

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.