Evidence map›Paper›PMID 35922891›Full record

SynthesisJournal of biomedical optics2022

Noninvasive hemoglobin sensing and imaging: optical tools for disease diagnosis.

Michaela Taylor-Williams, Graham Spicer, Gemma Bale, Sarah E Bohndiek

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of biomedical optics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Review
  3. Early Radiation Therapy Response Assessment Using Multi-Scale Photoacoustic Imaging.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  5. Review
  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Michaela Taylor-WilliamsUniversity of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom, United Kingdom.
Graham SpicerUniversity of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom, United Kingdom.
Gemma BaleUniversity of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom, United Kingdom.
Sarah E BohndiekUniversity of Cambridge, Department of Physics, Cavendish Laboratory, Cambridge, United Kingdom, United Kingdom.

Funding

Cancer Research UK 16267
6 · The paper itself

Abstract

significanceMeasurement and imaging of hemoglobin oxygenation are used extensively in the detection and diagnosis of disease; however, the applied instruments vary widely in their depth of imaging, spatiotemporal resolution, sensitivity, accuracy, complexity, physical size, and cost. The wide variation in available instrumentation can make it challenging for end users to select the appropriate tools for their application and to understand the relative limitations of different methods.

aimWe aim to provide a systematic overview of the field of hemoglobin imaging and sensing. APPROACH: We reviewed the sensing and imaging methods used to analyze hemoglobin oxygenation, including pulse oximetry, spectral reflectance imaging, diffuse optical imaging, spectroscopic optical coherence tomography, photoacoustic imaging, and diffuse correlation spectroscopy.

resultsWe compared and contrasted the ability of different methods to determine hemoglobin biomarkers such as oxygenation while considering factors that influence their practical application.

conclusionsWe highlight key limitations in the current state-of-the-art and make suggestions for routes to advance the clinical use and interpretation of hemoglobin oxygenation information.

Indexed as

HemoglobinsOximetrySpectrum AnalysisTomography, Optical CoherenceHemoglobinshemoglobinimagingsensingspectroscopy

Identifiers

PMID35922891
PMCPMC9346606

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.