Evidence map›Paper›PMID 35922836›Full record

Observational studyBMC pediatrics2022

The variation of antenatal corticosteroids administration for the singleton preterm birth in China, 2017 to 2018.

Qing Wang, Siyuan Jiang, Xuefeng Hu, Chao Chen, Yun Cao, Shoo Kim Lee, Jiang-Qin Liu, Reduction of Infection in Neonatal Intensive Care Units using the Evidence-based Practice for Improving Quality (REIN-EPIQ) Study Group

Open access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Qing WangDepartment of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, #2699, Gaoke western Road, Pudong District, Shanghai, 201204, China.
Siyuan JiangDepartment of Neonatology, Children's Hospital of Fudan University, #399, Wanyuan Road, Minghang District, Shanghai, 201102, China.
Xuefeng HuDepartment of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, #2699, Gaoke western Road, Pudong District, Shanghai, 201204, China.
Chao ChenDepartment of Neonatology, Children's Hospital of Fudan University, #399, Wanyuan Road, Minghang District, Shanghai, 201102, China.
Yun CaoDepartment of Neonatology, Children's Hospital of Fudan University, #399, Wanyuan Road, Minghang District, Shanghai, 201102, China. yuncao@fudan.edu.cn.
Shoo Kim LeeMaternal-Infant Care Research Centre and Department of Pediatrics Mount Sinai Hospital, Department of Pediatrics, and #Department of Obstetrics and Gynecology and Dalla Lana School of Public Health, University of Toronto, 600 University Avenue, Room 19-231M, Toronto, ON, M5G 1X5, Canada. shoo.lee@sinaihealth.ca.
Jiang-Qin LiuDepartment of Neonatology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, #2699, Gaoke western Road, Pudong District, Shanghai, 201204, China. jiangqinliu@163.com.
Reduction of Infection in Neonatal Intensive Care Units using the Evidence-based Practice for Improving Quality (REIN-EPIQ) Study Group
Shanghai First Maternity and Infant Hospital · CNChildren's Hospital of Fudan University · CNMount Sinai Hospital · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe administration of antenatal corticosteroids (ACS) to women who are at risk of preterm birth has been proven to reduce not only the mortality, but also the major morbidities of the preterm infants. The rate of ACS and the risk factors associated with ACS use in Chinese population is unclear. This study aimed to investigate the rate of ACS use and the associated perinatal factors in the tertiary maternal centers of China.

methodsData for this retrospective observational study came from a clinical database of preterm infants established by REIN-EPIQ trial. All infants born at < 34 weeks of gestation and admitted to 18 tertiary maternal centers in China from 2017 to 2018 were enrolled. Any dose of dexamethasone was given prior to preterm delivery was recorded and the associated perinatal factors were analyzed.

resultsThe rate of ACS exposure in this population was 71.2% (range 20.2 - 92%) and the ACS use in these 18 maternal centers varied from 20.2 to 92.0% in this period. ACS exposure was higher among women with preeclampsia, caesarean section delivery, antibiotic treatment and who delivered infants with lower gestational age and small for gestational age. ACS use was highest in the 28-31 weeks gestational age group, and lowest in the under 26 weeks of gestational age group (x

conclusionThe ACS exposure was variable among maternity hospitals and quality improvement of ACS administration is warranted.

Indexed as

Premature BirthAdrenal Cortex HormonesCesarean SectionFemaleGestational AgeHumansInfantInfant, NewbornInfant, PrematurePregnancyAdrenal Cortex HormonesAntenatal corticosteroidsBronchopulmonary dysplasiaNeonatal mortalityPerinatal factorsPreterm

Identifiers

PMID35922836
PMCPMC9347139
OpenAlexW4289711753

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.