Evidence map›Paper›PMID 35922820›Full record

ArticleBMC research notes2022

Finding the best fit for improving reproducibility: reflections from the QUEST Center for Responsible Research.

Natascha Drude, Lorena Martinez-Gamboa, Tamarinde Haven, Constance Holman, Martin Holst, Silke Kniffert, Sarah McCann, Torsten Rackoll, Robert Schulz, Sarah Weschke

Abstract readLetter
In one paragraph

Article in BMC research notes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Natascha DrudeQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-7153-2894
Lorena Martinez-GamboaQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-1120-4178
Tamarinde HavenQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany. tamarinde.haven@bih-charite.de.ORCID http://orcid.org/0000-0002-4702-2472
Constance HolmanQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-8075-2821
Martin HolstQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-8135-6265
Silke KniffertQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0001-5084-3960
Sarah McCannQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0003-4737-2349
Torsten RackollQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0003-2170-5803
Robert SchulzQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-4830-309X
Sarah WeschkeQUEST Center for Responsible Research, Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0003-2069-9245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Increasing the reproducibility and trustworthiness of biomedical research requires engaging stakeholders from all levels in an institutional setting. The QUEST Center for Responsible Research aims to develop and implement new approaches to improve the culture and practice of research, tailored to the needs of these stakeholders. Members of the QUEST Center organised a brainstorm to reflect on the challenges and new opportunities encountered in implementing different projects through QUEST and share the lessons that working groups have learned over the first five years. The authors informally surveyed and interviewed working groups where relevant and highlight common themes that have influenced the success of many projects, including top-down and bottom-up engagement, managing expectations, the availability of expertise, ensuring sustainability, and considering incentives. The commentary authors conclude by encouraging the research community to view initiatives that promote reproducibility not as a one-size-fits-all undertaking, but rather as an opportunity to unite stakeholders and customise drivers of cultural change.

Indexed as

Biomedical ResearchReproducibility of ResultsBehaviour changeInstitutionsReproducibilityResearch cultureResponsible researchStakeholders

Identifiers

PMID35922820
PMCPMC9351171

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.