Evidence map›Paper›PMID 35922726›Full record

ArticleAnnals of biomedical engineering2022

Piecewise Multivariate Linearity Between Kinematic Features and Cumulative Strain Damage Measure (CSDM) Across Different Types of Head Impacts.

Xianghao Zhan, Yiheng Li, Yuzhe Liu, Nicholas J Cecchi, Olivier Gevaert, Michael M Zeineh, Gerald A Grant, David B Camarillo

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Article in Annals of biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

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5citing papers in PubMed
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Xianghao Zhan *Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
Yiheng Li *Department of Biomedical Data Science, Stanford University, Stanford, CA, 94305, USA.
Yuzhe LiuDepartment of Bioengineering, Stanford University, Stanford, CA, 94305, USA. yuzheliu@stanford.edu.ORCID http://orcid.org/0000-0002-9451-0620
Nicholas J CecchiDepartment of Bioengineering, Stanford University, Stanford, CA, 94305, USA.
Olivier GevaertDepartment of Biomedical Data Science, Stanford University, Stanford, CA, 94305, USA.
Michael M ZeinehDepartment of Radiology, Stanford University, Stanford, CA, 94305, USA.
Gerald A GrantDepartment of Neurosurgery, Stanford University, Stanford, CA, 94305, USA.
David B CamarilloDepartment of Bioengineering, Stanford University, Stanford, CA, 94305, USA.

Funding

Disseminating a validated mouthguard sensor to investigate the effect of head impacts on brain healthR24NS098518 · NINDS · STANFORD UNIVERSITY · PI CAMARILLO, DAVID, GRANT, GERALD ARTHUR · 2018 to 2021
$1.1M
NIH HHS R24NS098518
6 · The paper itself

Abstract

In a previous study, we found that the relationship between brain strain and kinematic features cannot be described by a generalized linear model across different types of head impacts. In this study, we investigate if such a linear relationship exists when partitioning head impacts using a data-driven approach. We applied the K-means clustering method to partition 3161 impacts from various sources including simulation, college football, mixed martial arts, and car crashes. We found piecewise multivariate linearity between the cumulative strain damage (CSDM; assessed at the threshold of 0.15) and head kinematic features. Compared with the linear regression models without partition and the partition according to the types of head impacts, K-means-based data-driven partition showed significantly higher CSDM regression accuracy, which suggested the presence of piecewise multivariate linearity across types of head impacts. Additionally, we compared the piecewise linearity with the partitions based on individual features used in clustering. We found that the partition with maximum angular acceleration magnitude at 4706 rad/s

Indexed as

Brain ConcussionBrain InjuriesFootballAccelerationBiomechanical PhenomenaComputer SimulationHeadHumansClusteringImpact clustersKinematicsK-meansTraumatic brain injury

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.