Evidence map›Paper›PMID 35922602›Full record

SynthesisSurgical endoscopy2022

Endoscopy versus early surgery for the management of chronic pancreatitis: a systematic review and meta-analysis.

Umesha Boregowda, Juan Echavarria, Chandraprakash Umapathy, Laura Rosenkranz, Hari Sayana, Sandeep Patel, Shreyas Saligram

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Chronic Pancreatitis: Role of Endoscopic Procedures.Digestive diseases and sciences · 2026
    Review
  2. [Endoscopic Management of Chronic Pancreatitis].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2026
    Review
  3. Review
  4. Observational
  5. Current status and future perspectives for endoscopic treatment of local complications in chronic pancreatitis.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 2 countries.

Umesha BoregowdaDivision of Gastroenterology, Hepatology, and Nutrition, University of Texas Health, San Antonio, TX, 78229, USA.
Juan EchavarriaDivision of Gastroenterology, Hepatology, and Nutrition, University of Texas Health, San Antonio, TX, USA.
Chandraprakash UmapathyDivision of Gastroenterology, Hepatology, and Nutrition, University of Texas Health, San Antonio, TX, USA.
Laura RosenkranzDivision of Gastroenterology, Hepatology, and Nutrition, University of Texas Health, San Antonio, TX, USA.
Hari SayanaDivision of Gastroenterology, Hepatology, and Nutrition, University of Texas Health, San Antonio, TX, USA.
Sandeep PatelDivision of Gastroenterology, Hepatology, and Nutrition, University of Texas Health, San Antonio, TX, USA.
Shreyas SaligramDivision of Gastroenterology, Hepatology, and Nutrition, University of Texas Health, San Antonio, TX, USA. drsaligram@yahoo.com.ORCID http://orcid.org/0000-0002-6189-260X
The University of Texas Health Science Center at San Antonio · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimEndoscopic stone removal and stenting of pancreatic strictures are the initial treatment for treating chronic pancreatitis-related pain. Surgery is considered when endoscopic interventions fail to improve symptoms. In this meta-analysis, we have compared early surgery versus endoscopic interventions.

methodsThe study was performed as per the PRISMA statement. The literature search was conducted on online databases to identify studies that compared endoscopy and surgery for the management of chronic pancreatitis symptoms. Primary outcomes of interest were pain relief, complications, and exocrine/endocrine insufficiency. Secondary outcomes were mean length of stay and mean number of procedures. Pooled odds ratio (OR) was calculated using random-effects model with 95% confidence interval (CI).

resultsOf a total of 9880 articles that were screened, three randomized controlled trials and two retrospective studies with 602 patients (71.4% males) were found to be eligible. Endoscopic interventions were performed in 317 patients and 285 patients underwent early surgery. Early surgery provided significantly better pain relief compared to endoscopy (OR 0.46; 95%CI 0.27-0.80; p = 0.01; I

conclusionCompared to endoscopy, early surgery appears to be better in controlling chronic pancreatitis-related pain, with no significant difference in procedure-related complications. However, larger randomized controlled trials are needed to ascertain their efficacy.

Indexed as

Pancreatitis, ChronicEndoscopy, GastrointestinalFemaleHumansMalePainPain ManagementRetrospective StudiesChronic pancreatitisExtracorporeal shockwave lithotripsyPancreatectomyPancreatic sphincterotomyPancreatic stricturesPancreatojejunostomy

Identifiers

PMID35922602
OpenAlexW4289637465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.