Evidence map›Paper›PMID 35922601›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2023

Diffuse leptomeningeal glioneuronal tumor in an 8-year-old girl: case report and review of the literature.

Eduardo Cambruzzi, Mateus Scarabelot Medeiros, Carmo Eduardo Cardoso, Guilherme Alberto Germano Silva, Kelly Schlotte, Willian Pegoraro Kus

Abstract readReviewCase Reports
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Understanding diffuse leptomeningeal glioneuronal tumors.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Eduardo CambruzziFederal University of Rio Grande Do Sul, Porto Alegre, Rio Grande do Sul, Brazil. dudacambruzzi@yahoo.com.br.ORCID http://orcid.org/0000-0003-4101-9325
Mateus Scarabelot MedeirosConceição Hospital Group, Porto Alegre, Rio Grande do Sul, Brazil.
Carmo Eduardo CardosoConceição Hospital Group, Porto Alegre, Rio Grande do Sul, Brazil.
Guilherme Alberto Germano SilvaConceição Hospital Group, Porto Alegre, Rio Grande do Sul, Brazil.
Kelly SchlotteConceição Hospital Group, Porto Alegre, Rio Grande do Sul, Brazil.
Willian Pegoraro KusConceição Hospital Group, Porto Alegre, Rio Grande do Sul, Brazil.
Grupo Hospitalar Conceição · BRUniversidade Federal do Rio Grande · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse leptomeningeal glioneuronal tumors (DLGNTs) are rare central nervous system tumors of childhood that were recently described as a new entity. DLGNTs usually manifest with symptoms related to increased intracranial pressure or spinal cord compression. The classic radiological feature is a widespread leptomeningeal enhancement that may involve the entire neuroaxis. Microscopic examination demonstrates oligodendroglial-like cells that are positive for OLIG2, MAP2, and S100 and negative for IDH-1. Anaplastic features occur in some cases. Molecularly, DLGNTs are characterized by chromosome arm 1p deletion and alteration of a mitogen-activated protein kinase (MAPK) pathway gene, most commonly BRAF-KIAA1549 fusion. There is no established grading system for these tumors, which may have an indolent or aggressive behavior. Treatment usually involves chemotherapy and radiation therapy.

Indexed as

Brain NeoplasmsCentral Nervous System NeoplasmsMeningeal NeoplasmsChildFemaleHumansDiffuse leptomeningeal glioneuronal tumorLeptomeningeal neoplasmsNeurosurgeryPediatrics

Identifiers

PMID35922601
OpenAlexW4289667343

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.