ArticleNature2022
A non-canonical vitamin K cycle is a potent ferroptosis suppressor.
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Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 429 papers.
0numbers the graph read from it
0cells of the map it votes in
429citing papers in PubMed
61.3field-weighted citation impact, top 1% of its field
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
429 citing papers in PubMed, 641 citations in OpenAlex.
- Ferroptosis: significance to zoonotic diseases and therapeutic prospects.Emerging microbes & infections · 2026Review
- Arginine metabolism, polyamine homeostasis and ferroptosis in cancer: Molecular links and therapeutic opportunities (Review).Molecular medicine reports · 2026Review
- Article
- Gut Microbiota-Derived Short-Chain Fatty Acids Driven by N-Carbamylglutamate Alleviates Premature Ovarian Failure Through Suppressing Ferroptosis.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026Article
- Bilirubin and the Yellow Players in Ferroptosis: A Delicate Balance in Human Health and Disease, with a Focus on the Liver, Cardiovascular System, and Brain.Biomolecules · 2026Review
- Ferroptosis in kidney disease.Nature reviews. Nephrology · 2026Review
- Ferroptosis as a target mechanism in heart and kidney disease.The Journal of clinical investigation · 2026Review
- Article
- Subcellular regulation of ferroptosis: roles of individual intracellular organelles and cross talk.American journal of physiology. Cell physiology · 2026Review
- The irony of Parkinson's disease: Converging mechanisms of redox imbalance and ferroptosis.Redox biology · 2026Review
- Nano-formulations in therapeutic strategies targeting cancer ferroptosis.Journal of pharmaceutical analysis · 2026Review
- Cell Type-Specific Ferroptosis Regulatory Networks in the Bone Microenvironment: Implications for the Pathogenesis and Treatment of Osteoporosis.Traffic (Copenhagen, Denmark) · 2026Review
- Reactive Oxygen Species in Breast Cancer: From Redox Dysregulation to ROS-Responsive Therapeutics.Cell biochemistry and function · 2026Review
- AI-enhanced adaptive virtual screening of large libraries for ligand discovery.Nature biotechnology · 2026Article
- Vitamin K in brain metabolism and cognitive function: mechanistic evidence, human associations, and unresolved questions.Metabolic brain disease · 2026Review
- Ferroptosis in T cells: mechanisms, biology and translational opportunities.Nature reviews. Immunology · 2026Review
- Menaquinone-4 protects CD8Science China. Life sciences · 2026Article
- Review
- MK-4 Ameliorates Post-Ovulatory Aging of Mouse Oocytes by Alleviating Iron Metabolism Disorder-Induced Oxidative Stress.Molecular reproduction and development · 2026Article
- MiR-940 Suppresses Ferroptosis by Controlling Expression of Key Regulatory Genes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
369 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
27 authors at 6 institutions in 3 countries.
Eikan MishimaInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany. eikan@med.tohoku.ac.jp.ORCID http://orcid.org/0000-0002-3706-2745
Junya ItoLaboratory of Food Function Analysis, Tohoku University, Sendai, Japan.
Zijun WuDepartment of Chemistry and Biomolecular Science, University of Ottawa, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-5030-071X
Toshitaka NakamuraInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Adam WahidaInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Sebastian DollInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID http://orcid.org/0000-0002-8933-5362
Wulf TonnusUniversitätsklinikum Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0002-9728-1413
Palina NepachalovichInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Leipzig, Germany.ORCID http://orcid.org/0000-0002-3404-9537
Elke EggenhoferDepartment of Surgery, University Hospital Regensburg, University of Regensburg, Regensburg, Germany.
Maceler AldrovandiInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Bernhard HenkelmannInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Ken-Ichi YamadaPhysical Chemistry for Life Science Laboratory, Faculty of Pharmaceutical Sciences, Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0003-2100-8477
Jonas WanningerInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.
Omkar ZilkaDepartment of Chemistry and Biomolecular Science, University of Ottawa, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0003-3534-0470
Emiko SatoDivision of Clinical Pharmacology and Therapeutics, Tohoku University Graduate School of Pharmaceutical Sciences and Faculty of Pharmaceutical Sciences, Sendai, Japan.
Regina FeederleMonoclonal Antibody Core Facility, Helmholtz Zentrum München, Neuherberg, Germany.ORCID http://orcid.org/0000-0002-3981-367X
Daniela HassInstitute for Diabetes and Cancer, Helmholtz Zentrum München, Neuherberg, Germany.
Adriano MaidaInstitute for Diabetes and Cancer, Helmholtz Zentrum München, Neuherberg, Germany.
André Santos Dias MourãoInstitute of Structural Biology, Helmholtz Zentrum München, Neuherberg, Germany.
Andreas LinkermannUniversitätsklinikum Carl Gustav Carus Dresden, Technische Universität Dresden, Dresden, Germany.ORCID http://orcid.org/0000-0001-6287-9725
Edward K GeisslerDepartment of Surgery, University Hospital Regensburg, University of Regensburg, Regensburg, Germany.ORCID http://orcid.org/0000-0003-3661-6168
Kiyotaka NakagawaLaboratory of Food Function Analysis, Tohoku University, Sendai, Japan.
Takaaki AbeDivision of Nephrology, Rheumatology and Endocrinology, Tohoku University Graduate School of Medicine, Sendai, Japan.ORCID http://orcid.org/0000-0003-3170-4660
Maria FedorovaInstitute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, Leipzig University, Leipzig, Germany.
Bettina PronethInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany.ORCID http://orcid.org/0000-0002-4119-9437
Derek A PrattDepartment of Chemistry and Biomolecular Science, University of Ottawa, Ottawa, Ontario, Canada.ORCID http://orcid.org/0000-0002-7305-745X
Marcus ConradInstitute of Metabolism and Cell Death, Helmholtz Zentrum München, Neuherberg, Germany. marcus.conrad@helmholtz-muenchen.de.ORCID http://orcid.org/0000-0003-1140-5612
Helmholtz Zentrum München · DETohoku University · JPUniversity Hospital Carl Gustav Carus · DEUniversity of Ottawa · CAUniversity Hospital Regensburg · DEKyushu University · JP
Funding
European Research Council
Abstract
Ferroptosis, a non-apoptotic form of cell death marked by iron-dependent lipid peroxidation
Indexed as
FerroptosisVitamin KAntidotesAntioxidantsCarbon-Carbon LigasesCoenzymesHydroquinonesLipid PeroxidationOxidation-ReductionS100 Calcium-Binding Protein A4WarfarinAntidotesAntioxidantsCarbon-Carbon LigasesCoenzymesglutamyl carboxylasehydroquinoneHydroquinonesS100 Calcium-Binding Protein A4Vitamin KWarfarin
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.