Evidence map›Paper›PMID 35922062›Full record

ArticleJMIR research protocols2022

The Early Detection and Case Management of Skin Diseases With an mHealth App (eSkinHealth): Protocol for a Mixed Methods Pilot Study in Côte d'Ivoire.

Rie R Yotsu, Sakiko Itoh, Koffi Aubin Yao, Kouamé Kouadio, Kazuko Ugai, Yao Didier Koffi, Diabate Almamy, Bamba Vagamon, Ronald E Blanton

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05300399 (MIND-the-SKIN Project), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05300399 naunknown statusnot on this map

MIND-the-SKIN Project: Multi-functional Innovative Digital Toolkit for the Skin Diseases in LMICs and Beyond

TypeinterventionalSponsorTulane UniversityRan2022 to 2023Enrolled1,364ConditionsSkin DiseasesArmsmHealth app
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Observational
  2. Buruli ulcer: An epidemiological update from Japan.The Journal of dermatology · 2025
    Review
  3. Case Report: Cutaneous Leishmaniasis-A Hidden Disease in Côte d'Ivoire.The American journal of tropical medicine and hygiene · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 4 countries.

Rie R YotsuDepartment of Tropical Medicine, Tulane School of Public Health and Tropical Medicine, New Orleans, LA, United States.ORCID https://orcid.org/0000-0001-9102-1912
Sakiko ItohDepartment of Genome Informatics, Graduate School of Medicine, Osaka University, Suita, Japan.ORCID https://orcid.org/0000-0002-1711-208X
Koffi Aubin YaoHope Commission International, Abidjan, Cote D'Ivoire.ORCID https://orcid.org/0000-0001-8105-2539
Kouamé KouadioPasteur Institute, Abidjan, Cote D'Ivoire.ORCID https://orcid.org/0000-0002-7722-2387
Kazuko UgaiSchool of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan.ORCID https://orcid.org/0000-0003-3731-927X
Yao Didier KoffiCentre Suisse de Recherches Scientifiques en Côte d'Ivoire, Abidjan, Cote D'Ivoire.ORCID https://orcid.org/0000-0001-9128-5555
Diabate AlmamyDepartment of Dermatology, Universite Alassane Ouattara, Bouaké, Cote D'Ivoire.ORCID https://orcid.org/0000-0002-1098-7465
Bamba VagamonDepartment of Dermatology, Universite Alassane Ouattara, Bouaké, Cote D'Ivoire.ORCID https://orcid.org/0000-0001-9641-5187
Ronald E BlantonDepartment of Tropical Medicine, Tulane School of Public Health and Tropical Medicine, New Orleans, LA, United States.ORCID https://orcid.org/0000-0001-6655-7336
Tulane University · USUniversité Alassane Ouattara · CIInstitut Pasteur · FRNagasaki University · JPSwiss Centre for Scientific Research · CIThe University of Osaka · JP

Funding

MIND-the-SKIN Project: Multi-functional Innovative Digital Toolkit for the Skin Diseases in LMICs and BeyondR33TW011860 · FIC · TULANE UNIVERSITY OF LOUISIANA · PI YOTSU, RIE · 2023 to 2025
$902k
MIND-the-SKIN Project: Multi-functional Innovative Digital Toolkit for the Skin Diseases in LMICs and BeyondR21TW011860 · FIC · TULANE UNIVERSITY OF LOUISIANA · PI YOTSU, RIE · 2021 to 2022
$356k
FIC NIH HHS R21 TW011860FIC NIH HHS R33 TW011860
6 · The paper itself

Abstract

backgroundThere is a high prevalence of skin diseases sub-Saharan Africa, including skin neglected tropical diseases (NTDs) that could lead to lifelong disabilities and deformities if not diagnosed and treated early. To achieve early detection and early treatment of these skin diseases, we developed a mobile health app, eSkinHealth.

objectiveThis paper outlines a protocol for evaluating the effect of our eSkinHealth app in the early detection and effective management of skin diseases in Côte d'Ivoire.

methodsA mixed methods pilot trial will be conducted in Côte d'Ivoire and will consist of 3 phases: (1) the development and improvement of the eSkinHealth app, (2) a pilot trial to evaluate the usability of the eSkinHealth app for local medical staff in Côte d'Ivoire, and (3) a pilot trial to evaluate the effectiveness of early detection and case management of targeted skin NTDs (Buruli ulcer, leprosy, yaws, and lymphatic filariasis) with the eSkinHealth app in Côte d'Ivoire. The pilot study will be implemented as a 2-arm trial with local health care providers and patients with skin NTDs over a 3-month follow-up period. The local health care providers will be assigned to an intervention group receiving the eSkinHealth app to be used in their daily practices or a control group. Training will be provided on the use and implementation of the app and the diagnostic pipeline to the intervention group only, while both groups will receive training on skin diseases. Our primary outcome is to evaluate the early detection and effective management of skin diseases using the eSkinHealth app in Côte d'Ivoire by the number of cases diagnosed and managed. Additionally, we will evaluate the eSkinHealth app with validated questionnaires and in-depth interviews. Procedures of our methods have been reviewed and approved by the Institutional Review Board of the Ministry of Health, Côte d'Ivoire and by Tulane University in 2021.

resultsThis study was funded in 2021. We started the enrollment of patients in February 2022, and data collection is currently underway. We expect the first results to be submitted for publication in 2023.

conclusionsOur eSkinHealth app is a field-adapted platform that could provide both direct diagnostic and management assistance to health workers in remote settings. The study will provide evidence for the usability and the effectiveness of the eSkinHealth app to improve the early detection and case management of skin NTDs in Côte d'Ivoire and, furthermore, is expected to contribute to knowledge on mobile health approaches in the control of skin NTDs.

trial registrationClinicalTrials.gov NCT05300399; https://clinicaltrials.gov/ct2/show/study/NCT05300399. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/39867.

Indexed as

neglected diseasesremote consultationskin diseasesskin NTDsteledermatologytelemedicine

Identifiers

PMID35922062
PMCPMC9536527
OpenAlexW4288755001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.