ArticleBrain and language2022
White matter microstructural integrity pre- and post-treatment in individuals with chronic post-stroke aphasia.
Article in Brain and language, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 15 citations in OpenAlex.
- Surgery versus Botulinum Toxin A for Treatment of Post-Stroke Upper-Limb Spasticity: White Matter Changes, Function, and Quality-of-Life-A Randomized Controlled Trial.Neural plasticity · 2026Trial
- Microstructural properties in subacute aphasia: concurrent and prospective relationships underpinning recovery.Brain structure & function · 2024Trial
- White matter predictors of cerebellar tDCS treatment effects in aphasia rehabilitation.Frontiers in neurologyTrial
- Right hemisphere involvement in intensive aphasia therapy outcomes: a multimodal neuroimaging concept study.Journal of neurology · 2026Article
- Tractography-based correlation of diffusion anisotropy metrics in chronic post-stroke aphasia.BMC medical imaging · 2026Article
- Diffusion Tensor Imaging and Advanced Diffusion Imaging in Post-Stroke Aphasia Recovery.Tomography (Ann Arbor, Mich.) · 2026Review
- Network flexibility facilitates treatment-induced recovery in post-stroke aphasia.Brain communications · 2026Article
- Article
- Using unsupervised dimensionality reduction to identify lesion patterns predictive of post-stroke aphasia severity.Cortex; a journal devoted to the study of the nervous system and behavior · 2025Article
- Charting the Course of Aphasia Recovery: Factors, Trajectories, and Outcomes.Annual review of linguistics · 2025Article
- Early subacute frontal callosal microstructure and language outcomes after stroke.Brain communications · 2025Article
- The role of language-related functional brain regions and white matter tracts in network plasticity of post-stroke aphasia.Journal of neurology · 2024Review
- Disentangling neuroplasticity mechanisms in post-stroke language recovery.Brain and language · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
While previous studies have found that white matter damage relates to impairment severity in individuals with aphasia, further study is required to understand the relationship between white matter integrity and treatment response. In this study, 34 individuals with chronic post-stroke aphasia underwent behavioral testing and structural magnetic resonance imaging at two timepoints. Thirty participants within this sample completed typicality-based semantic feature treatment for anomia. Tractography of bi-hemispheric white matter tracts was completed via Automated Fiber Quantification. Associations between microstructural integrity metrics and behavioral measures were evaluated at the tract level and in nodes along the tract. Diffusion measures of the left inferior longitudinal, superior longitudinal, and arcuate fasciculi were related to aphasia severity and diffusion measures of the left inferior longitudinal fasciculus were related to naming and treatment response. This study also found preliminary evidence of left inferior longitudinal fasciculus microstructural changes following treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.