Evidence map›Paper›PMID 35921539›Full record

ArticleThe Journal of infectious diseases2022

Clinical Evaluation of Severe Acute Respiratory Syndrome Coronavirus 2 Rapid Antigen Tests During the Omicron Wave in South Africa.

Natasha Samsunder, Margaretha de Vos, Sinaye Ngcapu, Jennifer Giandhari, Lara Lewis, Ayesha B M Kharsany, Cherie Cawood, Tulio de Oliveira, Quarraisha Abdool Karim, Salim Abdool Karim and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Natasha SamsunderCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Margaretha de VosFIND, the Global Alliance for Diagnostics, Geneva, Switzerland.
Sinaye NgcapuCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Jennifer GiandhariKwaZulu-Natal Research Innovation and Sequencing Platform, Durban, South Africa.
Lara LewisCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Ayesha B M KharsanyCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Cherie CawoodEpicentre AIDS Risk Management, Durban, South Africa.
Tulio de OliveiraCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Quarraisha Abdool KarimCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Salim Abdool KarimCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Kogieleum NaidooCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.
Camille EscadafalFIND, the Global Alliance for Diagnostics, Geneva, Switzerland.
Aida SivroCentre for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa.ORCID 0000-0001-9215-5285
Centre for the AIDS Programme of Research in South Africa · ZAFIND · CHEpicentre (South Africa) · ZAUniversity of Washington · US

Funding

University of KwaZulu-Natal - CAPRISA HIV/AIDS Clinical Trials UnitUM1AI069469 · NIAID · UNIVERSITY OF KWAZULU-NATAL · PI QUARRAISHA ABDOOL KARIM · 2012 to 2026
$36.4M
6 · The paper itself

Abstract

We evaluated the performance of nasal and nasopharyngeal Standard Q COVID-19 [coronavirus disease 2019] Ag tests (SD Biosensor) and the Panbio COVID-19 Ag Rapid Test Device (nasal; Abbott) against the Abbott RealTime severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) assay during the Omicron (clades 21M, 21K, and 21L) wave in South Africa. Overall, all evaluated tests performed well, with high sensitivity (range, 77.78%-81.42%) and excellent specificity values (>99%). The sensitivity of rapid antigen tests increased above 90% in samples with cycle threshold <20, and all 3 tests performed best within the first week after symptom onset.

Indexed as

COVID-19SARS-CoV-2Antigens, ViralCOVID-19 TestingHumansSensitivity and SpecificitySouth AfricaAntigens, Viral21K/BA121L/BA2antigenCOVID-19OmicronSARS-CoV-2sensitivityspecificity

Identifiers

PMID35921539
PMCPMC9384653
OpenAlexW4289653730

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.