Evidence map›Paper›PMID 35921538›Full record

ArticleEuropean heart journal. Cardiovascular Imaging2023

Right atrial function and fibrosis in relation to successful atrial fibrillation ablation.

Luuk H G A Hopman, Julia E Visch, Pranav Bhagirath, Anja M van der Laan, Mark J Mulder, Orod Razeghi, Michiel J B Kemme, Steven A Niederer, Cornelis P Allaart, Marco J W Götte

Open access · hybridAbstract readComment
In one paragraph

Article in European heart journal. Cardiovascular Imaging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Review
  18. In Silico TRials guide optimal stratification of ATrIal FIbrillation patients to Catheter Ablation and pharmacological medicaTION: the i-STRATIFICATION study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Luuk H G A HopmanDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Julia E VischDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Pranav BhagirathDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Anja M van der LaanDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Mark J MulderDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Orod RazeghiDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Michiel J B KemmeDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Steven A NiedererDivision of Imaging Sciences and Biomedical Engineering, King's College London, London, UK.
Cornelis P AllaartDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Marco J W GötteDepartment of Cardiology, Amsterdam UMC, Amsterdam, the Netherlands.
Amsterdam University of Applied Sciences · NLAmsterdam University Medical Centers · NLKing's College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsBi-atrial remodelling in patients with atrial fibrillation (AF) is rarely assessed and data on the presence of right atrial (RA) fibrosis, the relationship between RA and left atrial (LA) fibrosis, and possible association of RA remodelling with AF recurrence after ablation in patients with AF is limited. METHODS AND

resultsA total of 110 patients with AF undergoing initial pulmonary vein isolation (PVI) were included in the present study. All patients were in sinus rhythm during cardiac magnetic resonance (CMR) imaging performed prior to ablation. LA and RA volumes and function (volumetric and feature tracking strain) were derived from cine CMR images. The extent of LA and RA fibrosis was assessed from 3D late gadolinium enhancement images. AF recurrence was followed up for 12 months after PVI using either 12-lead electrocardiograms or Holter monitoring. Arrhythmia recurrence was observed in 39 patients (36%) after the 90-day blanking period, occurring at a median of 181 (interquartile range: 122-286) days. RA remodelling parameters were not significantly different between patients with and without AF recurrence after ablation, whereas LA remodelling parameters were different (volume, emptying fraction, and strain indices). LA fibrosis had a strong correlation with RA fibrosis (r = 0.88, P < 0.001). Both LA and RA fibrosis were not different between patients with and without AF recurrence.

conclusionsThis study shows that RA remodelling parameters were not predictive of AF recurrence after AF ablation. Bi-atrial fibrotic remodelling is present in patients with AF and moreover, the amount of LA fibrosis had a strong correlation with the amount of RA fibrosis.

Indexed as

Atrial FibrillationCatheter AblationAtrial Function, RightContrast MediaFibrosisGadoliniumHeart AtriaHumansRecurrenceTreatment OutcomeContrast MediaGadoliniumatrial fibrillationatrial fibrosisatrial remodellingcardiovascular magnetic resonance (CMR)

Identifiers

PMID35921538
PMCPMC9936834
OpenAlexW4289653941

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.