Evidence map›Paper›PMID 35921448›Full record

ArticleVeterinary medicine and science2022

Equine placental extract supplement as a night barking remedy in dogs with cognitive dysfunction syndrome.

Tatsuya Amano, Takashi Ikeda, Makiko Yamaguchi, Nobuhisa Kakehi, Keizo Hanada, Tsuyuko Watanabe, Kentarou Tahara, Eiichi Hirano

Open access · goldAbstract readCase Reports
In one paragraph

Article in Veterinary medicine and science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Tatsuya AmanoAmano Animal Hospital, Okayama, Japan.
Takashi IkedaMomo Animal Hospital, Kobe, Japan.
Makiko YamaguchiRui Animal Hospital, Tokoname, Japan.
Nobuhisa KakehiDomestic Sales Department, Japan Bio Products Co., Ltd., Shibuya, Japan.
Keizo HanadaMedical Affairs Department, Japan Bio Products Co., Ltd., Shibuya, Japan.
Tsuyuko WatanabeMedical Affairs Department, Japan Bio Products Co., Ltd., Shibuya, Japan.
Kentarou TaharaMedical Affairs Department, Japan Bio Products Co., Ltd., Shibuya, Japan.
Eiichi HiranoResearch Institute, Japan Bio Products Co., Ltd., Kurume, Japan.ORCID 0000-0002-8607-1488
Japan Bio Products (Japan) · JPFujita Animal Hospital · JPKuma Hospital · JPOkayama University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the aging of pet dogs, there has been an increasing trend in senility-related diseases; additionally, cognitive disorders accompanied by abnormal behaviours are a major burden for owners. Recently, there have been a series of consultations regarding the fact that night barking, which is an abnormal behaviour, remarkably interferes with the owner's sleep and adversely affects the owner's quality of life. However, there has been no effective solution to this problem. In this study, three aged pet dogs diagnosed with dementia were administered an equine placental extract (eqPE) as pet supplement, which has been shown in laboratory models to improve cognitive function. Consequently, night barking ceased 1 week after the administration of eqPE in case 2 and it was observed to decrease in the other two dogs. Furthermore, night barking disappeared 2 and 3 weeks after the administration of eqPE in cases 1 and 3, respectively. No recurrence or exacerbation of night barking was observed in the three cases treated with the eqPE, and no adverse events were observed. These results suggest that eqPE may be useful for improving night barking in pet dogs with dementia, and it is expected to be a new treatment method.

Indexed as

Cognitive DysfunctionDementiaDog DiseasesHorse DiseasesPlacental ExtractsAnimalsDogsFemaleHorsesPlacentaPregnancyQuality of LifePlacental Extractsbarking at nightcanine cognitive dysfunction syndromeplacental extractsenior pet caresupplement

Identifiers

PMID35921448
PMCPMC9514492
OpenAlexW4289637873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.