Evidence map›Paper›PMID 35921135›Full record

ArticleJournal of medical Internet research2022

A Questionnaire-Based Ensemble Learning Model to Predict the Diagnosis of Vertigo: Model Development and Validation Study.

Fangzhou Yu, Peixia Wu, Haowen Deng, Jingfang Wu, Shan Sun, Huiqian Yu, Jianming Yang, Xianyang Luo, Jing He, Xiulan Ma and 8 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Journal of medical Internet research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. A digital neurotology history: Characteristics and inter-rater reliability.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  3. Article
  4. Article
  5. Automated vertigo diagnosis using video-oculography and artificial intelligence for clinic-based triage: Preliminary results.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  6. Article
  7. [Artificial intelligence applications in Ménière's disease].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Review
  8. Article
  9. Neurological update: neuro-otology 2023.Journal of neurology · 2023
    Article
  10. Machine Learning-Based Dizziness/Vertigo Disease Diagnosis by Combining Medical History and Signs.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Fangzhou Yu *Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-1549-0327
Peixia Wu *Nursing Department, Eye & ENT Hospital, Fudan University, Shanghai, China.ORCID 0000-0003-4946-4140
Haowen Deng *Department of Information Management and Information Systems, Fudan University, Shanghai, China.ORCID 0000-0001-5373-3003
Jingfang WuDepartment of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-5743-1990
Shan SunNational Health Commission Key Laboratory of Hearing Medicine, Fudan University, Shanghai, China.ORCID 0000-0003-2142-4307
Huiqian YuDepartment of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-5769-9583
Jianming YangDepartment of Otorhinolaryngology-Head and Neck Surgery, The Second Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID 0000-0002-2996-399X
Xianyang LuoDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital, Medical College, Xiamen University, Xiamen, China.ORCID 0000-0003-1542-6832
Jing HeDepartment of Otolaryngology-Head and Neck Surgery, The First Affiliated Hospital, Medical College, Xiamen University, Xiamen, China.ORCID 0000-0002-7320-4587
Xiulan MaDepartment of Otolaryngology-Head and Neck Surgery, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0002-0364-9206
Junxiong WenDepartment of Otolaryngology-Head and Neck Surgery, Shengjing Hospital of China Medical University, Shenyang, China.ORCID 0000-0002-9031-5916
Danhong QiuDepartment of Otolaryngology, Shanghai Pudong Hospital, Shanghai, China.ORCID 0000-0003-2827-3185
Guohui NieDepartment of Otolaryngology, Shenzhen Second People's Hospital, Shenzhen, China.ORCID 0000-0002-8328-3864
Rizhao LiuDepartment of Otolaryngology, Shenzhen Second People's Hospital, Shenzhen, China.ORCID 0000-0002-4748-1775
Guohua HuDepartment of Otolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0002-9550-2534
Tao ChenDepartment of Otolaryngology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.ORCID 0000-0003-2872-6287
Cheng Zhang *Department of Information Management and Information Systems, Fudan University, Shanghai, China.ORCID 0000-0002-8277-5138
Huawei Li *Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.ORCID 0000-0002-9788-9285
Fudan University · CNChina Medical University · CNEye & ENT Hospital of Fudan University · CNFirst Affiliated Hospital of Xiamen University · CNShenzhen Second People's Hospital · CNThe Affiliated Yongchuan Hospital of Chongqing Medical University · CNAnhui Medical University · CNPudong Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuestionnaires have been used in the past 2 decades to predict the diagnosis of vertigo and assist clinical decision-making. A questionnaire-based machine learning model is expected to improve the efficiency of diagnosis of vestibular disorders.

objectiveThis study aims to develop and validate a questionnaire-based machine learning model that predicts the diagnosis of vertigo.

methodsIn this multicenter prospective study, patients presenting with vertigo entered a consecutive cohort at their first visit to the ENT and vertigo clinics of 7 tertiary referral centers from August 2019 to March 2021, with a follow-up period of 2 months. All participants completed a diagnostic questionnaire after eligibility screening. Patients who received only 1 final diagnosis by their treating specialists for their primary complaint were included in model development and validation. The data of patients enrolled before February 1, 2021 were used for modeling and cross-validation, while patients enrolled afterward entered external validation.

resultsA total of 1693 patients were enrolled, with a response rate of 96.2% (1693/1760). The median age was 51 (IQR 38-61) years, with 991 (58.5%) females; 1041 (61.5%) patients received the final diagnosis during the study period. Among them, 928 (54.8%) patients were included in model development and validation, and 113 (6.7%) patients who enrolled later were used as a test set for external validation. They were classified into 5 diagnostic categories. We compared 9 candidate machine learning methods, and the recalibrated model of light gradient boosting machine achieved the best performance, with an area under the curve of 0.937 (95% CI 0.917-0.962) in cross-validation and 0.954 (95% CI 0.944-0.967) in external validation.

conclusionsThe questionnaire-based light gradient boosting machine was able to predict common vestibular disorders and assist decision-making in ENT and vertigo clinics. Further studies with a larger sample size and the participation of neurologists will help assess the generalization and robustness of this machine learning method.

Indexed as

Machine LearningSurveys and QuestionnairesVertigoAdultFemaleHumansMaleMiddle AgedProspective StudiesReproducibility of Resultsdiagnostic modelENTmachine learningquestionnairevertigovestibular disorders

Identifiers

PMID35921135
PMCPMC9386585
OpenAlexW4289593700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.