Evidence map›Paper›PMID 35920974›Full record

SynthesisHead and neck pathology2022

Clinical, Radiographic and Histopathological Analysis of Craniopharyngiomas and Ameloblastomas: A Systematic Review.

Luana Amorim Morais da Silva, Solimar Ribeiro Carlete Filho, Marcelo Jales Diniz Saraiva, Caio Rodrigues Maia, Camila Dannyelle Fernandes Dutra Pereira Santos, Pedro Paulo de Andrade Santos

Open access · greenAbstract readSystematic ReviewCase Reports
In one paragraph

Synthesis in Head and neck pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Association of MDM2 Overexpression in Ameloblastomas withInternational journal of molecular sciences · 2024
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Luana Amorim Morais da SilvaFederal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Solimar Ribeiro Carlete FilhoFederal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Marcelo Jales Diniz SaraivaFederal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Caio Rodrigues MaiaPostgraduate Program in Dental Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil.
Camila Dannyelle Fernandes Dutra Pereira SantosOnofre Lopes Hospital, Brazilian Hospital Services Company (EBSERH), Natal, RN, Brazil.
Pedro Paulo de Andrade SantosDepartment of Morphology, Biosciences Center, Federal University of Rio Grande do Norte (UFRN), Natal, RN, Brazil. ppdasantos@gmail.com.
Universidade Federal do Rio Grande do Norte · BRHospital Universitário Onofre Lopes · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCraniopharyngiomas and ameloblastomas are tumors of epithelial origin, mostly characterized by a benign course, slow growth and for being locally invasive. Some studies highlight the similarity of these neoplasms, especially regarding histopathological aspects. In this context, the aim of the present study was to carry out a systematic literature review correlating the clinical, radiographic, and histopathological aspects of these two tumors.

methodsSearches were conducted at the Pubmed, Periódicos Capes, Scopus, Science Direct, Web of Science and Scielo databases, according to the following inclusion criteria: publications in English or Spanish, from the 2000s and 2021, comprising case report studies, case series and literature reviews.

resultsConsidering clinical and radiographic aspects, it is evident that craniopharyngiomas and ameloblastomas exhibit few similarities. Histopathologically, however, adamantinomatous craniopharyngiomas are the type of tumor that most resembles ameloblastomas, both concerning the formation of palisade epithelial cords and epithelial formations. Regarding to recurrences in cases of craniopharyngioma, it appears that a more radical surgical resection is more related to a lower recurrence rate for both craniopharyngiomas and ameloblastomas. As for the outcome, it was observed that craniopharyngiomas have a greater relationship with possible systemic disorders.

conclusionsThis histopathological similarity is related to their origin, since both craniopharyngiomas and ameloblastomas share a relationship with the oral cavity, either partially, as in the case of craniopharyngiomas, or totally, as in ameloblastomas, not comprising the same lesion in different locations. It is important to note that the differential morphogenetic evidence observed herein between these lesions opens up a new field of study aiming at better treatment alternatives in the future.

Indexed as

NeoplasmsHumansAmeloblastomaCraniopharyngiomaNeoplasmPathological conditionsRadiography

Identifiers

PMID35920974
PMCPMC9729483
OpenAlexW4289550409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.