Evidence map›Paper›PMID 35920899›Full record

ArticleActa diabetologica2022

Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals.

Dominic Salamone, Giuseppina Costabile, Alessandra Corrado, Giuseppe Della Pepa, Marilena Vitale, Rosalba Giacco, Delia Luongo, Roberta Testa, Angela Albarosa Rivellese, Giovanni Annuzzi and 1 more

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In one paragraph

Article in Acta diabetologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Polysaccharide fromMetabolites · 2026
    Article
  4. Observational
  5. Article
  6. Observational
  7. Repairing gut barrier by traditional Chinese medicine: roles of gut microbiota.Frontiers in cellular and infection microbiology · 2024
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Dominic SalamoneDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Giuseppina CostabileDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Alessandra CorradoDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Giuseppe Della PepaDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Marilena VitaleDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Rosalba GiaccoInstitute of Food Science, National Research Council, 83100, Avellino, Italy.
Delia LuongoCNR- Institute of Biostructures and Bioimaging, 80100, Naples, Italy.
Roberta TestaDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Angela Albarosa RivelleseDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy. rivelles@unina.it.ORCID http://orcid.org/0000-0002-6525-9780
Giovanni AnnuzziDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Lutgarda BozzettoDepartment of Clinical Medicine and Surgery, "Federico II" University, Sergio Pansini, 5, 80131, Naples, Italy.
Federico II University Hospital · ITInstitute of Biostructure and Bioimaging · ITInstitute of Food Science · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimaim of the study was to evaluate serum short chain fatty acids (SCFA) concentrations in patients with Type 2 diabetes (T2D) and overweight/obese individuals.

methodsIn forty-three patients with T2D and twenty-eight overweight/obese patients SCFA were determined by Gas-Chromatography/Flame Ionization Detector (GC/FID).

resultsAcetic acid, propionic acid, butyric acid, and total SCFA were significantly reduced in T2D patients compared to overweight/obese in the unadjusted model. Adjusting for all variables only propionic acid remained significantly lower in T2D.

conclusionOnly reduction of propionic acid was closely related to diabetes itself, regardless of all other factors.

Indexed as

Diabetes Mellitus, Type 2PropionatesAcetic AcidButyric AcidFatty Acids, VolatileHumansObesityOverweightAcetic AcidButyric AcidFatty Acids, VolatilePropionatespropionic acidGut microbiotaObesityShort-chain fatty acidsType 2 diabetes

Identifiers

PMID35920899
OpenAlexW4289550470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.