Evidence map›Paper›PMID 35920558›Full record

ArticlemBio2022

Blockade of the Adenylate Cyclase Toxin Synergizes with Opsonizing Antibodies to Protect Mice against Bordetella pertussis.

Andrea M DiVenere, Dzifa Amengor, Rui P Silva, Jory A Goldsmith, Jason S McLellan, Jennifer A Maynard

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Outsmarting Pathogens with Antibody Engineering.Annual review of chemical and biomolecular engineering · 2023
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andrea M DiVenere *Department of Chemical Engineering, University of Texas, Austin, Texas, USA.
Dzifa Amengor *Department of Molecular Biosciences, University of Texas, Austin, Texas, USA.
Rui P SilvaDepartment of Molecular Biosciences, University of Texas, Austin, Texas, USA.
Jory A GoldsmithDepartment of Molecular Biosciences, University of Texas, Austin, Texas, USA.
Jason S McLellanDepartment of Molecular Biosciences, University of Texas, Austin, Texas, USA.ORCID 0000-0003-3991-542X
Jennifer A MaynardDepartment of Chemical Engineering, University of Texas, Austin, Texas, USA.ORCID 0000-0002-0363-8486
The University of Texas at Austin · USTexas Center for Infectious Disease · US

Funding

Structure, function and antigenicity of B. pertussis virulence factorsR01AI155453 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MAYNARD, JENNIFER A, MCLELLAN, JASON SCOTT · 2021 to 2025
$2.8M
Systematic evaluation of B. pertussis ACT’s role as a protective antigenR01AI122753 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI MAYNARD, JENNIFER A · 2016 to 2020
$1.9M
NIAID NIH HHS R01 AI122753NIAID NIH HHS R01 AI155453
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bordetella pertussisWhooping CoughAdenylate Cyclase ToxinAnimalsAntibodies, BacterialAntibodies, NeutralizingHumansInfantMiceOpsonin ProteinsPertussis VaccineVirulence Factors, BordetellaAdenylate Cyclase ToxinAntibodies, BacterialAntibodies, NeutralizingOpsonin ProteinsPertussis VaccineVirulence Factors, Bordetellaimmune evasionneutralizing antibodiespediatric infectious diseasepertussis toxins

Identifiers

PMID35920558
PMCPMC9426472
OpenAlexW4289550403

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.