Evidence map›Paper›PMID 35920536›Full record

ArticleeLife2022

Maternal H3K36 and H3K27 HMTs protect germline development via regulation of the transcription factor LIN-15B.

Chad Steven Cockrum, Susan Strome

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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    Article
  3. Review
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  5. Review
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  7. Article
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  9. Review
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Chad Steven CockrumDepartment of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, United States.ORCID https://orcid.org/0000-0002-4080-9184
Susan StromeDepartment of Molecular, Cell, and Developmental Biology, University of California, Santa Cruz, Santa Cruz, United States.ORCID https://orcid.org/0000-0001-9496-7412
University of California, Santa Cruz · US

Funding

IMMUNOLOGIC STUDY OF GERM GRANULES IN C. ELEGANS EMBRY0SR01GM034059 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI STROME, SUSAN · 1985 to 2020
$8.9M
Training Program/Molecular/Cell/Developmental BiologyT32GM008646 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI STROME, SUSAN · 1999 to 2018
$3.7M
Epigenetic transmission of germ cell fateF31GM125305 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI COCKRUM, CHAD STEVEN · 2018 to 2019
$76k
NIGMS NIH HHS F31 GM125305NIGMS NIH HHS R01 GM034059NIGMS NIH HHS T32 GM008646
6 · The paper itself

Abstract

Maternally synthesized products play critical roles in the development of offspring. A premier example is the

Indexed as

Caenorhabditis elegansCaenorhabditis elegans ProteinsAnimalsGene Expression Regulation, DevelopmentalGerm CellsPolycomb Repressive Complex 2Transcription FactorsCaenorhabditis elegans Proteinslin-15B protein, C elegansmes-2 protein, C elegansMes-4 protein, C elegansPolycomb Repressive Complex 2Transcription FactorsC. elegansdevelopmental biologyepigeneticsgenomicsgermlinematernal effect

Identifiers

PMID35920536
PMCPMC9348848
OpenAlexW4289544509

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.