Evidence map›Paper›PMID 35920197›Full record

ArticleActa biochimica et biophysica Sinica2022

Translesion synthesis of apurinic/apyrimidic site analogues by Y-family DNA polymerase Dbh from

Weiwei Wang, Huan Zhou, Li Peng, Feng Yu, Qin Xu, Qisheng Wang, Jianhua He, Xipeng Liu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta biochimica et biophysica Sinica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Weiwei WangShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Huan ZhouShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Li PengState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
Feng YuShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Qin XuShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Qisheng WangShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Jianhua HeShanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China.
Xipeng LiuState Key Laboratory of Microbial Metabolism, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China.
Shanghai Institute of Applied Physics · CNShanghai Jiao Tong University · CNChinese Academy of Sciences · CNUniversity of Chinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apurinic/apyrimidic (AP) sites are severe DNA damages and strongly block DNA extension by major DNA polymerases. Y-family DNA polymerases possess a strong ability to bypass AP sites and continue the DNA synthesis reaction, which is called translesion synthesis (TLS) activity. To investigate the effect of the molecular structure of the AP site on the TLS efficiency of Dbh, a Y-family DNA polymerase from

Indexed as

Sulfolobus acidocaldariusDNADNA DamageDNA-Directed DNA PolymeraseDNA RepairDNA ReplicationDNADNA-Directed DNA PolymeraseAP site analoguesDbhstranslesion synthesisY-family DNA polymerase

Identifiers

PMID35920197
PMCPMC9828665
OpenAlexW4225105903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.