Evidence map›Paper›PMID 35919999›Full record

ArticleProceedings. Biological sciences2022

A tale of two plasmids: contributions of plasmid associated phenotypes to epidemiological success among

P Malaka De Silva, George E Stenhouse, Grace A Blackwell, Rebecca J Bengtsson, Claire Jenkins, James P J Hall, Kate S Baker

Abstract read
In one paragraph

Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Surveillance of enteropathogenicJournal of medical microbiology · 2026
    Article
  2. Investigation of an outbreak ofMicrobial genomics · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

P Malaka De SilvaDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.ORCID 0000-0002-0579-0131
George E StenhouseDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
Grace A BlackwellEMBL-EBI, Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, CB101SA, UK.
Rebecca J BengtssonDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
Claire JenkinsGastro and Food Safety (One Health) Division, UK Health Security Agency (UKHSA), Colindale, London, UK.
James P J HallDepartment of Evolution, Ecology and Behaviour, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.ORCID 0000-0002-4896-4592
Kate S BakerDepartment of Clinical Infection, Microbiology and Immunology, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.

Funding

Biotechnology and Biological Sciences Research Council BB/V009184/1Medical Research Council MR/N013840/1Medical Research Council MR/R020787/1Wellcome Trust 106690/A/14/Z
6 · The paper itself

Abstract

Dissemination of antimicrobial resistance (AMR) genes by horizontal gene transfer (HGT) mediated through plasmids is a major global concern. Genomic epidemiology studies have shown varying success of different AMR plasmids during outbreaks, but the underlying reasons for these differences are unclear. Here, we investigated two

Indexed as

Drug Resistance, BacterialShigellaAnti-Bacterial AgentsGene Transfer, HorizontalPhenotypePlasmidsAnti-Bacterial Agentsantimicrobial resistancebacterial SOS responseconjugationplasmid fitness cost

Identifiers

PMID35919999
PMCPMC9346365

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.