Evidence map›Paper›PMID 35919979›Full record

ArticleJournal of the Royal Society, Interface2022

Liquid biopsies for early diagnosis of brain tumours:

Johanna A Blee, Xia Liu, Abigail J Harland, Kavi Fatania, Stuart Currie, Kathreena M Kurian, Sabine Hauert

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the Royal Society, Interface, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Liquid biopsy and glioblastoma.Exploration of targeted anti-tumor therapy · 2023
    Review
  2. Liquid biopsies for early diagnosis of brain tumours:Journal of the Royal Society, Interface · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Johanna A BleeEngineering Mathematics, Ada Lovelace Building, Bristol BS8 1TW, UK.ORCID 0000-0001-6873-0841
Xia LiuBrain Tumour Research Centre, Bristol Medical School, Bristol BS2 8DZ, UK.
Abigail J HarlandBrain Tumour Research Centre, Bristol Medical School, Bristol BS2 8DZ, UK.
Kavi FataniaDepartment of Radiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
Stuart CurrieDepartment of Radiology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK.
Kathreena M KurianBrain Tumour Research Centre, Bristol Medical School, Bristol BS2 8DZ, UK.
Sabine HauertEngineering Mathematics, Ada Lovelace Building, Bristol BS8 1TW, UK.
Brain Tumour Research · GBLeeds General Infirmary · GBUniversity of Bristol · GB

Funding

Cancer Research UK 28832Cancer Research UK 29019Cancer Research UK 29791Cancer Research UK C18281/A29019
6 · The paper itself

Abstract

Brain tumours are the biggest cancer killer in those under 40 and reduce life expectancy more than any other cancer. Blood-based liquid biopsies may aid early diagnosis, prediction and prognosis for brain tumours. It remains unclear whether known blood-based biomarkers, such as glial fibrillary acidic protein (GFAP), have the required sensitivity and selectivity. We have developed a novel

Indexed as

Brain NeoplasmsBiomarkersComputer SimulationEarly DiagnosisHumansLiquid BiopsyBiomarkersbiomarkersbrain tumourscancerglial fibrillary acidic protein (GFAP)glioblastoma multi-forme (GBM)mathematical modelling

Identifiers

PMID35919979
PMCPMC9346349
OpenAlexW4289526593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.