Evidence map›Paper›PMID 35919711›Full record

ArticleChemical science2022

Solution structure of a thrombin binding aptamer complex with a non-planar platinum(ii) compound.

Bo-Chen Zhu, Juan He, Xiao-Yu Xia, Jingxing Jiang, Wenting Liu, Liu-Yi Liu, Bing-Bing Liang, Hua-Gang Yao, Zhuofeng Ke, Wei Xia and 1 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Chemical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Bo-Chen ZhuMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China cesmzw@mail.sysu.edu.cn liuwenting@mail.sysu.edu.cn xiawei5@mail.sysu.edu.cn.
Juan HeSchool of Pharmaceutical and Chemical Engineering, Guangdong Pharmaceutical University Zhongshan 528458 China.
Xiao-Yu XiaMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China cesmzw@mail.sysu.edu.cn liuwenting@mail.sysu.edu.cn xiawei5@mail.sysu.edu.cn.
Jingxing JiangSchool of Materials Science and Engineering, PCFM Lab, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China kezhf3@mail.sysu.edu.cn.
Wenting LiuMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China cesmzw@mail.sysu.edu.cn liuwenting@mail.sysu.edu.cn xiawei5@mail.sysu.edu.cn.ORCID https://orcid.org/0000-0003-1461-3740
Liu-Yi LiuMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China cesmzw@mail.sysu.edu.cn liuwenting@mail.sysu.edu.cn xiawei5@mail.sysu.edu.cn.ORCID https://orcid.org/0000-0001-9467-5014
Bing-Bing LiangMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China cesmzw@mail.sysu.edu.cn liuwenting@mail.sysu.edu.cn xiawei5@mail.sysu.edu.cn.
Hua-Gang YaoSchool of Pharmaceutical and Chemical Engineering, Guangdong Pharmaceutical University Zhongshan 528458 China.
Zhuofeng KeSchool of Materials Science and Engineering, PCFM Lab, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China kezhf3@mail.sysu.edu.cn.ORCID https://orcid.org/0000-0001-9064-8051
Wei XiaMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China cesmzw@mail.sysu.edu.cn liuwenting@mail.sysu.edu.cn xiawei5@mail.sysu.edu.cn.ORCID https://orcid.org/0000-0001-6480-3265
Zong-Wan MaoMOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-sen University Guangzhou 510275 China cesmzw@mail.sysu.edu.cn liuwenting@mail.sysu.edu.cn xiawei5@mail.sysu.edu.cn.ORCID https://orcid.org/0000-0001-7131-1154
Sun Yat-sen University · CNGuangdong Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombin Binding Aptamer (TBA) is a monomolecular well-defined two G-tetrad antiparallel G-quadruplex DNA that inhibits the activity of human α-thrombin. In this report, we synthesized a quasi-cross-shaped platinum(ii) compound (L'

Identifiers

PMID35919711
PMCPMC9297526
OpenAlexW4285121255

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.